A cell stores all of its genetic material in its nucleus, in the form of chromosomes, but that's not all that's tucked away in there. The nucleus is also home to small bodies called nucleoli—clusters of proteins and RNA ...
Molecular & Computational biology
Nov 24, 2021
0
75
Researchers at University of California San Diego have produced a single-cell chromatin atlas for the human genome. Chromatin is a complex of DNA and protein found in eukaryotic cells; regions of chromatin at key gene regulatory ...
Molecular & Computational biology
Nov 12, 2021
0
304
New work led by Carnegie's Kangmei Zhao and Sue Rhee reveals a new mechanism by which plants are able to rapidly activate defenses against bacterial infections. This understanding could inspire efforts to improve crop yields ...
Plants & Animals
Oct 26, 2021
1
75
DNA, the hereditary material, interacts with proteins in the nuclei of cells to form a tightly packed complex with proteins, which is referred to as "chromatin." The molecular architecture of the chromatin regulates access ...
Cell & Microbiology
Oct 26, 2021
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97
Over time, many endogenous retrovirus (ERV) sequences have integrated into the human genome, and now play important roles in normal gene regulation.
Molecular & Computational biology
Oct 19, 2021
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5
Scientists from Tokyo Metropolitan University have uncovered a unique mechanism where two transcription factors stabilize each other's binding to DNA in fission yeast. They found that Atf1 and Rst2 help each other stably ...
Molecular & Computational biology
Sep 13, 2021
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49
The sensory cells in the inner ear and the touch receptors in the skin actually have a lot in common, according to a new study from the USC Stem Cell laboratory of Neil Segil published in the Proceedings of the National Academy ...
Cell & Microbiology
Jul 12, 2021
1
13
Northwestern Medicine scientists have developed a new method to analyze the protein composition of intact nucleosomes without losing combinatorial information present in chromatin. The technique, called Nuc-MS, could help ...
Biotechnology
May 24, 2021
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12
Mutations in two genetic regions in dogs explain over one third of the risk of developing an aggressive form of hematological cancer, according to a study led by Jacquelyn Evans and Elaine Ostrander at the National Human ...
Molecular & Computational biology
May 13, 2021
0
11
The DNA molecule is not naked in the nucleus. Instead, it is folded in a very organized way by the help of different proteins to establish a unique spatial organization of the genetic information. This 3D spatial genome organization ...
Cell & Microbiology
Apr 15, 2021
0
59
