A specific type of fat present in cell membranes also serves as a cellular pH sensor, a team of University of British Columbia researchers has discovered.
Aug 26, 2010
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The ability to combat some age-related diseases, such as cancer and diabetes, may rest with scientists unlocking clues about the molecular and cellular processes governing aging. The underlying theory is that if the healthy ...
Jul 07, 2010
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It is not unusual to hear people blame their metabolism after gaining a few pounds. But changes in metabolism - the process that shapes how our bodies turn food into energy -- can have much more sinister effects ...
Feb 18, 2010
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ATM, a protein that reacts to DNA damage by ordering repairs or the suicide of the defective cell, plays a similar, previously unknown role in response to oxidative damage outside of the nucleus, researchers report this week ...
Feb 18, 2010
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The complex chain of metabolic events in bacteria that lead to fatal diseases such as tuberculosis (TB) may be better understood using mathematical models, according to an article published in the February issue of Microbiology To ...
Feb 05, 2010
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In order to preserve our DNA, cells have developed an intricate system for monitoring and repairing DNA damage. Yet precisely how the initial damage signal is converted into a repair response remains unclear. Researchers ...
Dec 24, 2009
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Alzheimer's disease is caused by the build-up of a brain peptide called amyloid-beta. That's why eliminating the protein has been the focus of almost all drug research pursuing a cure for the devastating neurodegenerative ...
Nov 23, 2009
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The natural cycle of building bone to maintain skeletal strength and then breaking it down for the body's calcium needs is delicately balanced, but diseases like osteoporosis break down too much bone without adequate bone ...
Oct 07, 2009
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(PhysOrg.com) -- The NPC is the only way in or out of a cell's nucleus. It plays a key role in cellular metabolism and signaling, and any malfunction in these pores can have lethal consequences. Now new research reveals further ...
Sep 29, 2009
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A cellular protein that may prevent nerve cells from dying also helps to improve insulin action and lower blood glucose levels, according to a study by researchers at Albert Einstein College of Medicine of ...
Jul 22, 2009
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Researchers at McGill University and the University of Pennsylvania have discovered that a widely used anti-diabetic drug can boost the immune system and increase the potency of vaccines and cancer treatments. Their findings ...
Jun 03, 2009
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(PhysOrg.com) -- Embedded in our genes is a "clock" that regulates when we sleep, when we are awake and when we eat. This human clock manages what are known as circadian rhythms, 24-hour biological cycles ...
May 29, 2009
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A global analysis of brain proteins over a 10-week period in a mouse model of Huntington Disease has revealed some new insights into this complex neurodegenerative disorder. For example, profound changes (comparable to those ...
Apr 16, 2009
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Many diseases derive from problems with cellular respiration, the process through which cells extract energy from nutrients. Researchers at the Swedish medical university Karolinska Institutet have now discovered a new function ...
Apr 08, 2009
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Two University of Rhode Island scientists have revealed how a cancer causing protein is regulated by reactive oxygen species (ROS) -- a type of stress signal. Their findings provide new insight into how this protein normally ...
Mar 26, 2009
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