Catch and release: Collagen-mediated control of PEDF availability

Cells are like tiny self-contained machines that are constantly fine-tuned in response to both internal and external signals. Some of these signals are induced by extracellular ligands, specialized proteins that bind to specific ...

New technique tracks individual protein movement on live cells

The piece of gold that Richard Taylor was thrilled to track down weighed less than a single bacterium. Taylor, a postdoctoral fellow at the Max Planck Institute, was working to follow individual nanogold-labeled molecules ...

Designing and repurposing cell receptors

EPFL scientists have developed a computational method modeling and designing protein allostery that allows the accurate and rational engineering and even repurposing of cell receptors. The method can be a significant tool ...

'Dual login' mechanism found to resist fungal infection in cells

Indiana University researchers have identified a mechanism involving the body's ability to resist fungal infection. The work could help advance research on cancer therapies that use the body's own immune system to fight disease.

Researchers find new signaling systems in human cells

One-third of all approved drugs target the same family of receptors: the G-protein-coupled receptors (GPCRs). Now, researchers from the University of Copenhagen, along with two American labs, have expanded the known network ...

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