Pioneering automated proteoform imaging

Investigators led by Neil Kelleher, Ph.D., professor of Medicine in the Division of Hematology and Oncology and of Biochemistry and Molecular Genetics, have developed an automated technique for imaging and identifying proteoforms ...

Intercellular messengers reveal themselves

The cells in our body continuously keep each other informed. They do this by exchanging, among other things, virus-like vesicles. Pascale Zimmermann's group, from the Department of Human Genetics, has been studying these ...

Revealing structural secrets of a key cancer protein

Scientists have breathed new life into the study of a protein with an outsized link to human cancers because of its dangerous mutations, using advanced research techniques to detect its hidden regions.

Scientists unlock biological secrets of the aging process

How we grow old gracefully—and whether we can do anything to slow down the process—has long been a fascination of humanity. However, despite continued research the answer to how we can successfully combat aging still ...

Team develops key improvement to cryo-electron microscopy

The scientists who received the 2017 Nobel Prize in chemistry were honored for their development of a technique called cryo-electron microscopy, or cryo-EM. The technology was revolutionary because it enabled scientists to ...

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