Inside the protein channel that keeps bacteria alive

Almost all bacteria rely on the same emergency valves—protein channels that pop open under pressure, releasing a deluge of cell contents. It is a last-ditch effort, a failsafe that prevents bacteria from exploding and dying ...

Experimental evolution reveals how bacteria gain drug resistance

A research team at the RIKEN Center for Biosystems Dynamics Research (BDR) in Japan has succeeded in experimentally evolving the common bacteria Escherichia coli under pressure from a large number of individual antibiotics. ...

Researchers present insights in the search for new antibiotics

A collaborative research team from the University of Oklahoma, the Memorial Sloan Kettering Cancer Center and Merck & Co. published an opinion article in the journal, Nature Chemical Biology, that addresses the gap in the ...

Antibacterial prodrug by targeting intracellular metabolite

National University of Singapore researchers have developed an approach to selectively target pathogenic bacteria by harnessing an intracellular metabolite known as formate, abundant in these bacteria, as a new antimicrobial ...

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