A team of researchers affiliated with several institutions in France has found that amyloid fibrils lit with near-infrared radiation emit a dim, near-infrared signal. In their paper published in the journal Nature Photonics, ...
While amyloid plaques have long been closely associated with mechanisms driving Alzheimer's disease, visualizing how amyloid proteins assemble continues to prove difficult. The nanometer-sized amyloid fibrils are only a fraction ...
Optics & Photonics
Mar 26, 2019
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5
A team of researchers from Durham University in the U.K. and Shaanxi Normal University in China has discovered a type of protein that forms naturally into two main types of helical braids. In their paper published in the ...
Alzheimer's disease is caused by aggregates of amyloid-β (Aβ) peptides. This aggregation is accelerated at the cell membrane surface. Using molecular dynamics simulations and NMR experiments, the research group at ExCELLS ...
Biochemistry
Jan 2, 2019
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108
A new method of selectively binding proteins to nanoparticles has been described by a team of German and Chinese researchers headed by Prof. Bart Jan Ravoo, a chemist at the University of Münster (Germany). The nanoparticles ...
Biochemistry
Nov 21, 2018
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45
The century old mission to understand how the proteins responsible for amyloid-based diseases such as Alzheimer's, Huntingdon's and Parkinson's work has taken major steps forward in the last 12 months, thanks to a revolution ...
Biochemistry
Oct 30, 2018
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52
One of the hallmark traits of Alzheimer's disease, a debilitating disorder marked by memory deficits and general cognitive decline, is the accumulation in the brain of a protein called b-amyloid. These proteins form "plaques" ...
Biochemistry
Oct 23, 2018
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689
A 2016 study showed that exposure to urban pollution involving magnetite particles played a role in the development of Alzheimer's disease. It began from the hypothesis that magnetite particles would generate chemical reactions ...
Biochemistry
Oct 11, 2018
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9
Tiny protein structures called amyloids are key to understanding certain devastating age-related diseases. Aggregates, or sticky clumped-up amyloids, form plaques in the brain, and are the main culprits in the progression ...
Biochemistry
Aug 30, 2018
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23
Small interfering RNA sounds like something from a science fiction novel rather than a revolutionary type of medicine. But this odd-sounding new drug offers a novel strategy for treating disease by targeting the root cause ...
Biotechnology
Aug 17, 2018
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7
