Ancient medicinal clay shows promise against today's worst bacterial infections

January 26, 2016
UBC researchers Julian Davies and Shekooh Behroozian with a bucket of the clay. Credit: University of British Columbia.

Naturally occurring clay from British Columbia, Canada—long used by the region's Heiltsuk First Nation for its healing potential—exhibits potent antibacterial activity against multidrug-resistant pathogens, according to new research from the University of British Columbia.

The researchers recommend the rare mineral be studied as a clinical treatment for serious infections caused by ESKAPE strains of bacteria.

The so-called ESKAPE pathogens—Enterococcus faecium, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter species—cause the majority of U.S. hospital infections and effectively 'escape' the effects of antibacterial drugs.

"Infections caused by ESKAPE bacteria are essentially untreatable and contribute to increasing mortality in hospitals," says UBC microbiologist Julian Davies, co-author of the paper published today in the American Society for Microbiology's mBio journal.

"After 50 years of over-using and misusing antibiotics, ancient medicinals and other natural mineral-based agents may provide new weapons in the battle against multidrug-resistant pathogens."

The clay deposit is situated on Heiltsuk First Nation's traditional territory, 400 kilometres (250 miles) north of Vancouver, Canada, in a shallow five-acre granite basin. The 400-million kilogram (400,000 tonne) deposit was formed near the end of the last Ice Age, approximately 10,000 years ago.

Kisameet Bay, British Columbia. Credit: University of British Columbia.

Local First Nations people have used the clay for centuries for its therapeutic properties—anecdotal reports cite its effectiveness for ulcerative colitis, duodenal ulcer, arthritis, neuritis, phlebitis, skin irritation, and burns.

"We're fortunate to be able to partner with UBC on this significant research program" says Lawrence Lund, president of Kisameet Glacial Clay, a business formed to market cosmetic and medicinal products derived from the clay. "We hope it will lead to the development of a novel and safe antimicrobial that can be added to the diminished arsenal for the fight against the ESKAPE pathogens and other infection-related health issues plaguing the planet."

In the in vitro testing conducted by Davies and UBC researcher Shekooh Behroozian, clay suspended in water killed 16 strains of ESKAPE bacteria samples from sources including Vancouver General Hospital, St. Paul's Hospital, and the University of British Columbia's wastewater treatment pilot plant.

Shovel of clay from Kisameet Bay, British Columbia. Credit: University of British Columbia.

Explore further: Clay minerals are a possible new answer to MRSA and other 'superbug' infections

More information: Kisameet Clay Exhibits Potent Antibacterial Activity against the ESKAPE Pathogens, mBio American Society for Microbiology, January/February 2016 Volume 7 Issue 1 e01842-15

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krundoloss
5 / 5 (1) Jan 26, 2016
I hope the entire healthcare industry will get off of the whole "Synthetic Only" rules about medical treatment. They literally make it illegal to offer natural remedies at a 'treatment' for any 'disease'. It doesnt matter if the 'medicine' comes from natural or artificial sources, if it works, it works. We need to tear down the old system and build another where everything that works and helps with any disease, is explored, approved, and prescribed to patients. We need diets that are designed around our genetic profile, designed to give our bodies specifically what is needed, and to actively prevent any disease tendency that may show up in our genetic profile.
Whydening Gyre
not rated yet Jan 26, 2016
Might this be applied to patients with the "flesh-eating" bacteriums? Would be interesting to check...
Scroofinator
not rated yet Jan 26, 2016
We need to tear down the old system

Never will happen. The only thing we can do is expand on what we have to allow holistic and eastern medicines to become an actual scientifically backed alternative.
EyeNStein
5 / 5 (2) Jan 26, 2016
UBC missed the all important "how" which ASU scientists published earlier this month on the same clays:-

"one metallic element—chemically reduced iron, which in small amounts is required by a bacterial cell for nutrition—tricks the cell into opening its wall. Then another element, aluminium, props the cell wall open, allowing a flood of iron to enter the cell. This overabundance of iron then poisons the cell, killing it as the reduced iron becomes oxidized."

http://phys.org/n...ria.html

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