'Sifting' liquid at the molecular level: Method uses nanotubes to separate liquids

July 17, 2012

Drexel University engineers continue to drive research into the use of carbon nanotubes, straw-like structures that are more than 1,000 times thinner than a single human hair. Their most recent development uses the tiny tubes to separate liquids within a solution.

The researchers have shown that individual carbon nanotubes can act as a separation channel that would force two differing molecules to separate as easily as oil and water. For example, the molecules that comprise two chemically distinct will interact differently with the walls of the nanotube as the liquids flow through it. This will cause one of the liquids to drain through the nanoscale straw faster than the other, thus forcing a separation between the two liquids.

This technology could prove useful in a number of applications, including forensic studies with very small sample sizes and studying molecules extracted from individual cells. would be able to analyze trace evidence, even down to a single cell or invisible stains.

"We believe that this research will lead to development of tools for analysis on single living cells and push the limits of to even smaller scales and to single organelle columns," said Dr. Yury Gogotsi, director of the A.J. Drexel Nanotechnology Institute.

Gogotsi and Dr. Gary Friedman, director of the Drexel Plasma Medicine Lab and a professor of electrical and computer engineering, were the lead researchers on a study about applications of nanotubes for cellular chromatography that was recently published in Nature Publishing Group's Scientific Reports. The research was funded by a grant from W.M. Keck Foundation and the National Science Foundation's National Interdisciplinary Research Teams program.

The carbon nanotubes used in this study measure as small as 70 in outer diameter and are currently the smallest chromatography columns ever made. The columns are mechanically robust and are able to withstand repeated bending and compression. These characteristics are vital for applications at the cellular level, as the tiny tubes' durability allows them to penetrate cell membranes.

Continued nanotube research by Drexel engineers will examine the development of electrochemical and optical tools.

Explore further: Cells selectively absorb short nanotubes

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1 / 5 (1) Jul 18, 2012
Is it Maxwell's Demon?
not rated yet Jul 18, 2012
Nanotubes. Is there anything they CAN'T do?

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