Proteins do most of the real work in cells and are modified in accordance with functional requirements. An LMU team has now shown how proteins are chemically altered on the ribosome, even before they fold into the active ...
Cell & Microbiology
Dec 20, 2018
0
15
DNA-damaging agents, or "DDAs," make up the most widely used group of cancer drugs. Yet their therapeutic success has been curtailed by drug resistance—either present in cancer cells from the disease onset or arising during ...
Molecular & Computational biology
Oct 29, 2018
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48
A collaboration between three labs at UC San Francisco has resulted in an unprecedented look at a member of a vital and ubiquitous class of proteins called integrins (pronounced "INT-uh-grins"). Integrins are associated with ...
Biochemistry
Jul 31, 2018
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13
In recent years, it has become evident that the spatial organisation of the genome is key for its function. This depends on a number of factors, including the cohesin protein complex. This essential complex is present in ...
Cell & Microbiology
Jun 5, 2018
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62
Thumb through any old science textbook, and you'll likely find RNA described as little more than a means to an end, a kind of molecular scratch paper used to construct the proteins encoded in DNA.
Biotechnology
May 4, 2018
0
210
Detouring around a major research roadblock, researchers have found a new way to create valuable antibodies without needing ... llamas?
Cell & Microbiology
Feb 12, 2018
0
102
All the trillions of cells in our body share the same genetic information and are derived from a single, fertilized egg. When this initial cell multiplies during fetal development, its daughter cells become more and more ...
Cell & Microbiology
Jan 30, 2018
0
210
Researchers have applied Nobel prize-winning microscope technology to uncover an ion channel structure that could lead to new treatments for kidney stones. In a recent study published in Nature Structural and Molecular Biology, ...
Cell & Microbiology
Jan 2, 2018
0
20
Scientists of Helmholtz Zentrum München and Ludwig-Maximilians-Universität Munich (LMU) have discovered that two new classes of histone modifications couple cellular metabolism to gene activity. The study was published ...
Cell & Microbiology
Oct 24, 2017
0
10
A recently described variety of RNA closely associated with gene expression was found to be largely cell-type specific, raising the possibility this variety of RNA sequences may be able to be used as a marker in stem cell ...
Cell & Microbiology
Aug 30, 2017
0
28
