Scientists capture images of gene-editing enzymes in action
For the first time, scientists have captured high-resolution, three-dimensional images of an enzyme in the process of precisely cutting DNA strands.
Nature Structural & Molecular Biology is an integrated forum for structural and molecular studies. The journal places a strong emphasis on functional and mechanistic understanding of how molecular components in a biological process work together. Structural data may provide such insights, but they are not a pre-requisite for publication in the journal.
For the first time, scientists have captured high-resolution, three-dimensional images of an enzyme in the process of precisely cutting DNA strands.
Biotechnology
Jul 8, 2019
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398
(Phys.org) —A team of Canadian and Singaporean researchers has discovered that remnants of ancient viral DNA in human DNA must be present for pluripotency to occur in human stem cells. In their paper published in the journal ...
Researchers at UCLA's California NanoSystems Institute have become the first to produce images of the atomic structures of three specific biological nanomachines, each derived from a different potentially deadly bacterium—an ...
Bio & Medicine
Apr 21, 2015
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1793
Bacterial cells have an added layer of protection, called the cell wall, that animal cells don't. Assembling this tough armor entails multiple steps, some of which are targeted by antibiotics like penicillin and vancomycin.
Cell & Microbiology
Jan 11, 2017
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475
An international team of researchers have discovered a new and highly conserved site on the SARS-CoV-2 virus that can be neutralized by a specific antibody. Previous studies have reported that antibodies that block the virus ...
Cell & Microbiology
Aug 27, 2020
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606
A new study could explain why DNA and not RNA, its older chemical cousin, is the main repository of genetic information. The DNA double helix is a more forgiving molecule that can contort itself into different shapes to absorb ...
Cell & Microbiology
Aug 1, 2016
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1351
Enabling bioengineers to design new molecular machines for nanotechnology applications is one of the possible outcomes of a study by University of Montreal researchers that was published in Nature Structural and Molecular ...
Cell & Microbiology
Jun 10, 2012
13
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Touch a hot stove, and your fingers will recoil in pain because your skin carries tiny temperature sensors that detect heat and send a message to your brain saying, "Ouch! That's hot! Let go!"
Biochemistry
Jan 18, 2016
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1593
ASU scientists, together with collaborators from the Chinese Academy of Sciences in Shanghai, have published today, in Nature Structural and Molecular Biology, a first of its kind atomic level look at the enzyme telomerase ...
Cell & Microbiology
May 4, 2014
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Small stretches of DNA in the human genome are known as "pseudogenes" because, while their sequences are nearly identical to those of various genes, they have long been thought to be non-coding "junk" DNA.
Cell & Microbiology
Feb 24, 2013
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