Last update Sall4 is required for DNA repair in stem cells, 5 minutes ago
Cells control the adhesion protein desmoplakin by modifying the tail end of the protein, and this process goes awry in some patients with arrhythmogenic cardiomyopathy, according to a study in The Journal of ...
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A protein that helps embryonic stem cells (ESCs) retain their identity also promotes DNA repair, according to a study in The Journal of Cell Biology. The findings raise the possibility that the protein, Sall4, ...
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A new laboratory tool which will allow scientists to build and move microscopic cells could lead to the development of better treatments for disease.
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Bacteria that talk to one another and organize themselves into biofilms are more resistant to antibiotics. Researchers are now working to develop drugs that prevent bacteria from communicating.
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A powerful genome editing tool may soon become even more powerful. Researchers with the Lawrence Berkeley National Laboratory (Berkeley Lab) have unlocked the key to how bacteria are able to "steal" genetic ...
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A key factor in the biosynthesis and stable expression of multi-pass transmembrane proteins was discovered, and its loss is thought to cause retinal degeneration. The factor works especially for multi-pass ...
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Researchers at the University of York are part of a team of scientist that has discovered how bacteria can restart their 'outboard motor' by hotwiring their own genes.
Feb 27, 2015
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Scientists have captured the first detailed microscopy images of ultra-small bacteria that are believed to be about as small as life can get. The research was led by scientists from the U.S. Department of ...
Feb 27, 2015
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Sexual biology may be the key to uncovering why Anopheles mosquitoes are unique in their ability to transmit malaria to humans, according to researchers at Harvard T. H. Chan School of Public Health and University of Per ...
Feb 26, 2015
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Neuroscientists believe that the connectome, a map of each and every connection between the millions of neurons in the brain, will provide a blueprint that will allow them to link brain anatomy to brain function. ...
Feb 26, 2015
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Scientists at NYU Langone Medical Center and New York University have demonstrated that a specialized DNA-binding protein called CTCF is essential for the precise expression of genes that control the body plan of a developing ...
Feb 26, 2015
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A research team from Instituto Gulbenkian de Ciencia (IGC; Portugal), led by Florence Janody, in collaboration with Nicolas Tapon from London Research Institute (LRI; UK), discovered that the cell's skeleton ...
Feb 26, 2015
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Chemical changes - also known as epigenetic modifications - to messenger RNA (mRNA) are thought to play an important role in gene expression, and have recently been found to affect biological processes such as circadian clock ...
Feb 25, 2015
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A new study led by researchers at The Scripps Research Institute (TSRI) and the University of California (UC), San Diego School of Medicine shows that certain stem cell culture methods are associated with increased DNA mutations. ...
Feb 25, 2015
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Components of human endothelial cells stained for identification. In red is the 'actin' protein that allows the cells to move, adhere, divide and react to stimuli. In blue are the cell nuclei containing DNA.
Feb 25, 2015
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The therapeutic promise of human stem cells is indisputably huge, but the process of translating their potential into effective, real-world treatments involves deciphering and resolving a host of daunting complexities.
Feb 25, 2015
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Scientists have shed new light on the fundamental biological process of cell division, thanks to an emerging analytical method.
Feb 25, 2015
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Our guts literally teem with beneficial bacteria. But not all bacteria are harmless. Disease-causing bacteria, known as pathogens, can infect our intestines, causing illness or even death. Bacterial pathogens ...
Feb 24, 2015
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The ancestors of a large family of parasites—including those that cause malaria—were equipped to become parasites much earlier in their lineage than previously assumed, according to University of British Columbia (UBC) ...
Feb 24, 2015
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takes at least two motor proteins to tango, according to Rice University scientists who discovered the workhorses that move cargo in cells are highly sensitive to the proximity of their peers.
Feb 23, 2015
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Most people have taken an antibiotic to treat a bacterial infection. Now researchers from the University of North Carolina at Chapel Hill and the University of San Diego, La Jolla, reveal that the way we often think about ...
Feb 23, 2015
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It is well-known that bacteria can support each others' growth and exchange nutrients. Scientists at the Max Planck Institute for Chemical Ecology in Jena, Germany, and their colleagues at the universities ...
Feb 23, 2015
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Bacteria may not have brains, but they do have memories, at least when it comes to viruses that attack them. Many bacteria have a molecular immune system which allows these microbes to capture and retain ...
Feb 20, 2015
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Bacteria are masters in adapting to their environment. This adaptability contributes to the bacteria's survival inside their host. Researchers at the Vetmeduni Vienna now demonstrated that the bacterial pathogen ...
Feb 20, 2015
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Like a surgeon separating conjoined twins, cells have to be careful to get everything just right when they divide in two. Otherwise, the resulting daughter cells could be hobbled, particularly if they end ...
Feb 19, 2015
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Cellular biology still harbors mysteries. Notably, there is no unequivocal explanation behind endocytosis, the biological process that allows exchanges between a cell and its environment. Two hypotheses prevail ...
(Phys.org)—Two teams of researchers both working in the U.S. have announced new breakthroughs in better understanding how immunological memory works. Both teams have published their findings in the journal ...
"Alu" sequences are small repetitive elements representing about 10% of our genome. Because of their ability to move around the genome, these "jumping genes" are considered as real motors of evolution. However, they were ...
When federal funding regulations created limitations on human embryonic stem cell research, several states created their own funding programs. A new study analyzed stem cell funding programs in four states that provided their ...
The typical Escherichia coli, the laboratory rat of microbiology, is a tiny 1-2 thousandths of a millimeter long. Now, by blocking cell division, two researchers at Concordia University in Montreal have g ...
(Phys.org)—Photonic quantum technologies – including cryptography, enhanced measurement and information processing – face a conundrum: They require single photons, but these are difficult to create, ...
A team of researchers at Google has been looking into ways to change the way links are retrieved by its famous search engine—instead of ranking them based on popularity, the researchers are looking into ...
Most of the times we have looked at Uranus, it has seemed to be a relatively calm place. Well, yes its atmosphere is the coldest place in the solar system. But, when we picture the seventh planet in our ...
Drawing inspiration from veterinary medicine, researchers at the University of Washington have helped developed a new prospective approach to diagnosing tuberculosis (TB) - easy-to-obtain oral swab samples, ...
On the road to Walgett a sign welcomes visitors: "Farming is not a way of life, it keeps everyone alive." But with drought taking a heavy toll on the region, farming has become a battle for survival.
US space transportation company SpaceX launched two commercial communications satellites atop a Falcon 9 rocket Sunday evening.
Building a space telescope is no mean feat. Conditions here on Earth are drastically different from those experienced in orbit around our planet. How do we know that any telescope built in our controlled ...
No one wants to have child who is born underweight, but for numerous reasons, this may be unavoidable. An intriguing research report involving rats suggests that helping fetuses achieve optimal weight before birth is of even ...
What if one day, your computer, TV or smart phone could process data with light waves instead of an electrical current, making those devices faster, cheaper and more sustainable through less heat and power ...
Norwegian mammals and birds have many different methods of surviving long, intense winter nights. A biologist from the Norwegian University of Science and Technology (NTNU) University Museum reveals their ...
Ludwig Maximilian University of Munich researchers report the discovery of a new mechanism used by pathogenic bacteria to disable host defenses: Addition of a sugar residue at a specific position within the ...
Every year, drug-resistant infections kill more than 50,000 people across Europe and the United States, and hundreds of thousands more around the world. According to the Review on Antimicrobial Resistance ...
A new study suggests that bacteria may be able to jump between host species far easier than was previously thought. Researchers discovered that a single genetic mutation in a strain of bacteria infectious ...
New research shows that a burst of evolutionary innovation in the genes responsible for electrical communication among nerve cells in our brains occurred over 600 million years ago in a common ancestor of ...
A new family of bacteria that are common in malaria mosquitoes has been described by researchers at Swedish University of Agricultural Sciences (SLU) and Uppsala University in Sweden, Justus-Liebig-Universität ...
A particular gastrointestinal disorder, which causes colic, or abdominal pain, in horses, is more prevalent in Lancashire compared with other nearby counties, according to researchers at Lancaster University and the University ...
What happens when a chemical engineer and a physicist walk into a bar? They forge a collaboration that could change biological imaging.
(Phys.org)—A team of researches affiliated with several institutions in Japan has conducted research into the cellular structure of tight junctions in the small intestine, and has made progress in better ...
Pancreatic cancer and its metastases might have their days numbered, according to a study published in The Journal of Experimental Medicine.
Walk down the aisles of any food supplement store and you'll see that the use of nitrate supplements by athletes and fitness buffs has been popular for years. The hope is that these supplements will increase endurance (and ...
New research from North Carolina State University and Bucknell University finds that strong, reliable anti-retaliation policies can encourage employees to notify internal authorities of possible wrongdoing, but that offering ...
Australia's Parliamentary Joint Committee on Intelligence & Security (PJCIS) last week endorsed the data retention bill, which means we're all suspects now. ...
Researchers from institutions including Lund University have taken a step closer to producing solar fuel using artificial photosynthesis. In a new study, they have successfully tracked the electrons' rapid transit through ...
Tackling brain inflammation ameliorates Alzheimer's disease (AD), according to a study published in The Journal of Experimental Medicine.
An on-board air filtration system developed specifically for school buses reduces exposure to vehicular pollutants by up to 88 percent, according to a study by researchers at the UCLA Fielding School of Public ...
Scientists have moved closer to understanding why cancer cells can be so resilient, even when faced with the onslaught of nearly toxic drug cocktails, radiation, and even our own immune systems. A new research report appearing ...
Taking commonly used medications with anticholinergic effects is associated with a significantly higher risk for developing pneumonia in a study of more than 3,000 older Group Health patients living in the community—not ...
A slick new documentary on China's environmental woes has racked up more than 175 million online views in two days, underscoring growing concern in the country over the impact of air, water and soil pollution.
Defying scepticism and geek-stigma, mobile phone firms are determined this year to sell you a wristwatch wirelessly connected to your mobile phone.
Australia has developed something of an allergic reaction to any mention of uranium or nuclear energy. Blessed as we are with abundant reserves of coal, oil and gas, we have never had to ask the hard questions ...
Cancer patients with limited brain metastases (one to four tumors) who are 50 years old and younger should receive stereotactic radiosurgery (SRS) without whole brain radiation therapy (WBRT), according to a study available ...
InterDigital, Inc., a mobile technology research and development company, nanoelectronics research center imec, and WiGig chip developer Peraso Technologies Inc. today announced the integration of their respective technologies ...
Tomorrow's factory jobs will be completely different from those of today. Although they will continue to be organized around assembly stations, they will not work in rigid shifts, be subject to inflexible ...
A camera-trapping survey carried out by Fauna & Flora International (FFI) in north-west Liberia has yielded a number of interesting results, including the country's only footage of elephants filmed outside ...
Facing a challenge akin to solving a 1,000-piece jigsaw puzzle while blindfolded—and without touching the pieces—many structural biochemists thought it would be impossible to determine the atomic structure ...
With apologies to the late NASA legend Neil Armstrong, whose boots were the first to step onto the surface of the moon, you might describe Chandran Sabanayagam's research at the Delaware Biotechnology Institute ...
The principle of adaptation—the gradual modification of a species' structures and features—is one of the pillars of evolution. While there exists ample evidence to support the slow, ongoing process that ...
Microbes, small and ancient life forms, play a key role in maintaining life on Earth. As has often been pointed out, without microbes, we'd die—without us, most microbes would get along just fine.
Using a comprehensive analysis of RNA expression in different cell types, scientists from the RIKEN-led FANTOM5 consortium have made major strides toward resolving an outstanding mystery in biology. In the ...
Climate prognoses for 100 years or weather forecasts for tomorrow: The more precisely and continuously data are measured, the better will the prognosis be. KIT runs a number of stationary and mobile measurement ...
(Phys.org)—It was an interesting week for physics research—most of the big news was centered around space, the cosmos or how things came to be as they are. One team of physicists offered a solution to the puzzle of the origin of matter in the universe—suggesting t ...
(Phys.org)—Light behaves both as a particle and as a wave. Since the days of Einstein, scientists have been trying to directly observe both of these aspects of light at the same time. Now, scientists at ...
(Phys.org)—Graphene nanoribbons formed into a three-dimensional aerogel and enhanced with boron and nitrogen are excellent catalysts for fuel cells, even in comparison to platinum, according to Rice University ...
A British firm on Monday launched plans to build a giant lagoon off the southern Welsh coast that would harness the tide to provide electricity for the whole of Wales.
With the aid of X-ray crystallography, researchers at the University of Michigan have revealed the structures of two closely related enzymes that play essential roles in the body's ability to metabolize excess ...
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