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New enzyme atlas rewrites decades of biology research

WEHI researchers have led a major global effort to create the first authoritative atlas for a class of enzymes that regulate almost every cellular process in the human body. Published in Cell, the study establishes the first ...

Bacteria invent another way to turn on genes

In their landmark 1961 paper on the lac operon, Nobel laureates François Jacob and Jacques Monod speculated that RNA might control gene activity in bacteria through base-pairing interactions. But once protein transcription ...

New technique reveals body-wide cellular processes

Understanding gene expression within the body has been a boon for 21st century biology and therapeutics, but most discoveries that use these technologies only focus on one organ or one small area of tissue. At the University ...

Why cells respond 'incorrectly' in old age

Some of the signs of aging in human cells originate in the cell nucleus, because the packaged form of DNA changes with age. This has now been demonstrated by PSI researchers. It means that older cells can no longer react ...

New antibiotic alternative fights foodborne Salmonella

Antimicrobial-resistant Salmonella poses severe challenges to global food safety and public health. Researchers from China have now identified a novel bacteriophage that offers a highly promising "green" biocontrol solution ...

How the body senses cold has been a mystery—until now

When you reach into a bucket of ice, open your front door on a snowy day, or feel the tingle of menthol toothpaste, a protein in your nerve cells called TRPM8 springs into action, opening like a tiny gate to send a "cold" ...

Alternative pathways in proteasome biogenesis deciphered

A new study conducted by researchers from the University of Potsdam and the University of Cologne has deciphered the step-by-step assembly of the eukaryotic proteasome. Eukaryotes are organisms whose cells have a clearly ...

More news

Cell & Microbiology
Agricultural soils exposed to controversial weedkiller may be unexpected breeding ground for hospital 'superbugs'
Evolution
Stolen chloroplasts maintained by host-made proteins offer clues to plant cell origins
Cell & Microbiology
New imaging technique maps membrane lipids in 3D at nanoscale
Cell & Microbiology
The truth of timekeeping lies within: Key developments in understanding circadian rhythms
Cell & Microbiology
Python scales host microstructures that block bacterial biofilms—revealing potential for antimicrobial materials
Cell & Microbiology
New findings on the first steps in protein synthesis
Plants & Animals
Wildflower folk remedy shows modern potential for tackling antibiotic resistance
Cell & Microbiology
Study reshapes understanding of interaction between organelles in animal cells
Ecology
Drought spurs rise in antibiotic-resistant soil microbes
Cell & Microbiology
One step closer to deciphering TOR, the molecular machinery that makes humans and yeast grow
Cell & Microbiology
Engineered E. coli can monitor arsenic, offering a cheap biosensor
Cell & Microbiology
CryoPRISM: A new tool for observing cellular machinery in a more natural environment
Cell & Microbiology
Mining a methane-degrading bioreactor for protein rubies
Cell & Microbiology
Single-cell sequencing reveals unexpected protist diversity
Cell & Microbiology
From slices to whole bodies: How 3D cell atlases could reshape pathology research
Cell & Microbiology
High-pressure freezing boosts cell survival with less cryoprotectant, study shows
Cell & Microbiology
A lysosome switch could reshape research on cancer and neurodegenerative disease
Cell & Microbiology
Measuring irreversibility in gene transcription
Cell & Microbiology
Light-based technique creates artificial structures that mimic the scaffolding of cells
Cell & Microbiology
Chemo-optogenetic tool uses vitamin B₁₂ and green light to precisely regulate cell communication

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Biochemistry
Supercomputer simulations map spliceosome motions in a two-million-atom human cell model
Archaeology
Scandinavia's largest 'burial mound' may be a monument to catastrophe, not a king
General Physics
Human brain operates near, but not at, the critical point
Evolution
Ancient DNA reveals earliest known dogs lived alongside Ice Age humans
General Physics
Lab-based mini-atmosphere reveals how turbulence changes on different scales
Analytical Chemistry
AI-driven framework uncovers new carbon structures—one thought to be harder than diamond
Earth Sciences
North Sea wind farms may be reshaping sediment flows by 1.5 million tons a year
Archaeology
Ancient DNA finds 15,800-year-old dogs in Anatolia, buried like humans
Soft Matter
Liquids can fracture like solids—researchers discover the breaking point
Earth Sciences
Alaska analysis shows continued loss of Arctic landfast sea ice
Earth Sciences
Study explains Antarctic sea ice growth and sudden decline
Other
Saturday Citations: Birthday cetaceans; quantifying children's play experiences; placebos still effective
Space Exploration
Artemis II astronauts arrive at Florida launch site for first moon trip in 53 years
Astronomy
JWST solves decades-long mystery about why Saturn appears to change its spin
Earth Sciences
Major volcanic eruptions might be driven by gas dissolving back into magma
Archaeology
Scientists testing new scanning technology discover mysterious structure beneath an ancient Egyptian city
Earth Sciences
Japan's giant caldera volcano is refilling 7,300 years later
Plants & Animals
How lifetime stress drives abnormal behaviors in lab monkeys
General Physics
Piezoelectric materials enable a new approach to searching for axions
Biochemistry
Microwave carrots, air-fry tomatoes: Researchers identify sustainable cooking methods for better nutrition

Mining a methane-degrading bioreactor for protein rubies

Scientists have found a new type of iron-storing protein in a mixture of microbes containing methane-degraders. This discovery underscores the importance of characterizing proteins from microbes that cannot be isolated, thereby ...

Measuring irreversibility in gene transcription

Living cells are fundamentally nonequilibrium systems, meaning they constantly spend energy through seemingly one-way, irreversible processes, such as transcribing DNA into RNA, to keep life going. But how that irreversibility ...