A new control system for synthetic genes

Using an approach based on CRISPR proteins, MIT researchers have developed a new way to precisely control the amount of a particular protein that is produced in mammalian cells.

New yeast model can improve protein production

Microorganisms, such as baker's yeast, can be used as cell factories to produce different chemicals and proteins, such as commonly used pharmaceuticals as insulin. By modifying the cell factories researchers are trying to ...

Study describes new way of generating insulin-producing cells

Researchers at Karolinska Institutet in Sweden show how a molecule that they have identified stimulates the formation of new insulin-producing cells in zebrafish and mammalian tissue, through a newly described mechanism for ...

Stabilizing chromosomes to tackle tumors

Cells use RNA as a versatile tool to regulate the activity of their genes. Small snippets of RNA can fine-tune how much protein is produced from various genes; some small RNAs can shut genes off altogether. An enzyme called ...

Hungry yeast are tiny, living thermometers

Membranes are crucial to our cells. Every cell in your body is enclosed by one. And each of those cells contains specialized compartments, or organelles, which are also enclosed by membranes.

The role of ribosomes in age-related diseases

Aging leads to a decline in cellular fitness and loss of optimal protein function. Many age-related ailments, including Alzheimer's and Parkinson's diseases, are caused by protein aggregation, a result of errors in protein ...

Better in pairs: Proteins can help one another bind to DNA

Scientists from Tokyo Metropolitan University have uncovered a unique mechanism where two transcription factors stabilize each other's binding to DNA in fission yeast. They found that Atf1 and Rst2 help each other stably ...

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