Targeting Nsp1 protein could be a pathway for COVID-19 therapy
A study that identifies how a coronavirus protein called Nsp1 blocks the activity of genes that promote viral replication provides hope for new COVID-19 treatments.
A study that identifies how a coronavirus protein called Nsp1 blocks the activity of genes that promote viral replication provides hope for new COVID-19 treatments.
Molecular & Computational biology
Feb 16, 2021
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Since the beginning of the pandemic, scientists worldwide have been working intensely to precisely characterize the novel SARS-CoV2 virus. Only by understanding in detail how the virus is constructed and how it replicates ...
Cell & Microbiology
Feb 1, 2021
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540
Scientists have created a new way to detect the proteins that make up the pandemic coronavirus, as well as antibodies against it. They designed protein-based biosensors that glow when mixed with components of the virus or ...
Biochemistry
Jan 28, 2021
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544
A chemical probe molecule—a "first gen" molecule that can be used for drug development—that targets a host cell's protein quality control pathways can dramatically reduce infection by Dengue and Zika viruses. The research ...
Cell & Microbiology
Jan 27, 2021
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Editor's note: In this interview, Nathan Ahlgren, assistant professor of biology at Clark University, uses 3-D-printed models to explain what proteins do in viruses, how they interact with human cells, how the vaccine delivers ...
Cell & Microbiology
Jan 26, 2021
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A new study, involving the University of Cambridge and led by the Pirbright Institute, has identified key genetic changes in SARS-CoV-2—the virus that causes COVID-19—that may be responsible for the jump from bats to ...
Cell & Microbiology
Jan 11, 2021
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The emergence of a new variant of coronavirus has sparked renewed interest in the part of the virus known as the spike protein.
Cell & Microbiology
Dec 23, 2020
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21
Coronaviruses like the one that causes COVID-19 are studded with protein "spikes" that bind with receptors on the cells of their victims—the first step in infection. Now scientists have made the first detailed images of ...
Biochemistry
Dec 18, 2020
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693
A team led by UT Southwestern researchers has identified a key gene necessary for cells to consume and destroy viruses. The findings, reported online today in Nature, could lead to ways to manipulate this process to improve ...
Cell & Microbiology
Dec 16, 2020
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The binding of a SARS-CoV-2 virus surface protein spike—a projection from the spherical virus particle—to the human cell surface protein ACE2 is the first step to infection that may lead to COVID-19 disease. Penn State ...
Cell & Microbiology
Dec 9, 2020
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135