How our eyes detect and respond to changes in light intensity is determined by specialized cells in the eye called photoreceptors. In addition to converting light into electrical signals, effectively allowing us to see, rod-shaped ...
Biotechnology
Nov 20, 2019
0
140
Australian researchers are among the first in the world to have access to a new approach to understand intricate changes that control how proteins function in our cells in health and disease.
Analytical Chemistry
Aug 14, 2019
0
20
As sessile organisms, plants have to continually adapt their growth and architecture to the ever-changing environment. To do so, plants have evolved distinct molecular mechanisms to sense and respond to the environment and ...
Plants & Animals
Apr 28, 2022
0
94
The molecular mechanism underlying enzyme activity regulation of ubiquitin-specific protease 8 (USP8) has been decoded by researchers at Tokyo Tech. USP8 has been implicated in Cushing's disease pathogenesis. They have identified ...
Molecular & Computational biology
Nov 26, 2021
0
73
Influenza and other viruses pack their genetic material into a protein shell, which must be disassembled for the viruses to efficiently replicate. But how viruses "uncoat" their genes remains largely unknown. Now, Friedrich ...
Cell & Microbiology
Jan 3, 2024
0
3
In a study published in The Plant Cell, researchers led by Li Yunhai at the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences described a role for the endoplasmic reticulum (ER)–associated ...
Cell & Microbiology
Feb 10, 2023
0
22
A team of scientists under the lead of Ivan Dikic, Director of the Institute of Biochemistry II at Goethe University Frankfurt, has now discovered a novel mechanism of ubiquitination, by which Legionella bacteria can seize ...
Cell & Microbiology
Dec 1, 2016
0
8
Spartin, a protein linked to the neuronal disease Troyer syndrome, was thought to function in endocytosis. In the March 23, 2009 issue of the Journal of Cell Biology, Eastman et al. identify an unexpected role for Spartin ...
Cell & Microbiology
Mar 23, 2009
0
0
Researchers have identified a protein complex that marks misfolded proteins, stops them from interacting with other proteins in the cell, and directs them toward disposal. In collaboration with the neurology department at ...
Cell & Microbiology
Mar 27, 2019
0
40
Human cells have a sophisticated regulatory system that consists of labeling proteins with the small molecule ubiquitin. In a first, a team from the Technical University of Munich (TUM) has succeeded in marking proteins with ...
Biochemistry
Apr 4, 2019
0
14
