Scientists have described an improved, cost-efficient method to isolate membrane proteins, a class of proteins that are the targets of more than 60 percent of approved therapeutic drugs.
Cell & Microbiology
Jul 25, 2016
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5
Knowledge of the minute details of the proteins that are linked to diseases is crucial if we are to discover therapeutic targets and thus pave the way for possible treatments. Such knowledge gains even more relevance when ...
Biochemistry
Jun 10, 2016
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14
Researchers at the Max F. Perutz Laboratories of the University of Vienna and the Medical University of Vienna as well as at the University of Natural Resources and Life Sciences (BOKU) in Vienna have discovered an entirely ...
Biotechnology
Jun 11, 2015
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17
Scientists at the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), a part of the National Institutes of Health, have demonstrated that DNA previously thought to be "junk" plays a critical role ...
Cell & Microbiology
Dec 11, 2012
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0
Chromatin remodeling—the packaging and unpackaging of genomic DNA and its associated proteins—regulates a host of fundamental cellular processes including gene transcription, DNA repair, programmed cell death as well ...
Biochemistry
Nov 29, 2012
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0
Molecules with potent bioactivity alone are not suitable for new medicines. They must behave well inside the body, being easily absorbed, yet metabolically stable, once circulating through the blood stream. Adding fluorine ...
Materials Science
Oct 5, 2012
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UT Southwestern Medical Center researchers have identified compounds that appear to inhibit a signaling pathway in Huntington's disease, a finding that may eventually lead to a potential drug therapy to help slow the progression ...
Biochemistry
Jun 23, 2011
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0
The Aurora A kinase may contribute to polycystic kidney disease (PKD) by inactivating a key calcium channel in kidney cells, according to a study in the June 13 issue of The Journal of Cell Biology.
Cell & Microbiology
Jun 13, 2011
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Scientists from the Florida campus of The Scripps Research Institute have uncovered a potentially important new therapeutic target that could prevent stress-related cell death, a characteristic of neurodegenerative diseases ...
Biochemistry
Jun 2, 2011
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Molecular farming is an easy, fast, and safe method for producing vaccines and therapeutic proteins in plants. Now a team of Fraunhofer researchers from the USA has built up a Good Manufacturing Practices (GMP) compliant ...
Biotechnology
Jun 11, 2013
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