Researchers at Brigham and Women's Hospital have discerned that different tissue functions arise from a core biological machinery that is largely shared across tissues, rather than from their own individual regulators. In ...
Cell & Microbiology
Oct 27, 2017
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2
Researchers at Indiana University Bloomington have uncovered previously hidden steps of a gene silencing process used to combat viruses and other would-be genome invaders.
Cell & Microbiology
Feb 6, 2023
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11
The addition and removal of methyl groups on DNA plays an important role in gene regulation. In order to study these mechanisms more precisely, a German team has developed a new method by which specific methylation sites ...
Biochemistry
Nov 24, 2020
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19
An interdisciplinary team of researchers from North Carolina State University and University of California, Davis has developed a modeling algorithm that is able to identify genes associated with specific biological functions ...
Biotechnology
Sep 29, 2015
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32
Scientists at the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), a part of the National Institutes of Health, have demonstrated that DNA previously thought to be "junk" plays a critical role ...
Cell & Microbiology
Dec 11, 2012
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0
The tumor suppressor protein p53 has been dubbed the "guardian of the genome" because it protects the DNA from stress or long-term damage by regulating the expression of numerous genes involved DNA repair, cell division and ...
Molecular & Computational biology
Jun 30, 2023
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50
Bioengineers can tailor the genomes of cells to create "cellular therapies" that fight disease, but they have found it difficult to design specialized activating proteins called transcription factors that can throw the switch ...
Cell & Microbiology
Aug 14, 2023
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1
Researchers at the Max F. Perutz Laboratories of the University of Vienna and the Medical University of Vienna as well as at the University of Natural Resources and Life Sciences (BOKU) in Vienna have discovered an entirely ...
Biotechnology
Jun 11, 2015
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17
Blood cells originate from a small pool of hematopoietic stem cells (HSCs) through a complex process of differentiation steps that are tightly regulated at the transcriptional level. Dissecting the mechanisms underlying this ...
Cell & Microbiology
Oct 5, 2012
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0
New laboratory techniques can identify which of our genes are influenced by DNA snippets that are left behind in our genetic code by viruses, a new study finds.
Biotechnology
Dec 13, 2018
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