It's long been known that the proteins that package DNA, like students at a high school dance, require a chaperone. But what exactly that guardian looks and acts like has been a mystery—until now.
Molecular & Computational biology
Nov 27, 2019
0
378
The DNA of a single cell is two to three meters long end-to-end. To fit in the nucleus and function correctly, DNA is packaged around specialized proteins. These DNA-protein complexes are called nucleosomes, and they are ...
Biotechnology
Nov 21, 2019
0
126
A research team from the MIPT Center for Molecular Mechanisms of Aging and Age-Related Diseases has collaborated with colleagues from the U.S., Canada, France, and Germany to determine the spatial structure of the CysLT1 ...
Biochemistry
Oct 9, 2019
0
125
A new study by chemists at the University of Arkansas shows that X-ray crystallography, the standard method for determining the structure of proteins, can provide inaccurate information about a critical set of proteins—those ...
Biochemistry
Oct 8, 2019
0
94
For the first time, researchers have captured images of the formation of individual viruses, offering a real-time view into the kinetics of viral assembly. The research provides new insights into how to fight viruses and ...
Cell & Microbiology
Oct 3, 2019
0
74
In basic biology, medical sciences and pharmaceutical sciences, structural analyses of membrane proteins are important, and single-particle analysis by cryoEM is now very powerful method. Japanese researchers have developed ...
Biotechnology
Oct 3, 2019
0
14
Proteins are huge molecules that often have complex three-dimensional structure and morphology that can include side chains, folds, and twists. This three-dimensional shape is often the determining factor of their function ...
Biochemistry
Sep 16, 2019
0
15
Microtubules are protein polymers that assemble into dynamic structures, essential for cell division, shape, motility, and transport of intracellular cargos.
Cell & Microbiology
Sep 9, 2019
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5
Researchers from Oxford University have worked out the molecular structure of a protein that is vital for survival of the flu virus. Recently published in Nature, they used several different techniques to look at the arrangement ...
Biotechnology
Sep 6, 2019
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64
Steadily and relentlessly, the bacterium that causes gonorrhea has slipped past medicine's defenses, acquiring resistance to once-reliable drugs, including penicillin, tetracycline, and ciprofloxacin. These former stalwarts ...
Biochemistry
Aug 23, 2019
0
124
