Advances in microscopy have enabled researchers to picture loops of DNA strands for the first time. The images reveal how the human genome organizes itself in three-dimensional space at much higher resolution than previously ...
Biotechnology
Jul 22, 2021
0
377
Researchers from Osaka University have found that the attachment of a ubiquitin molecule to a protein called PCNA at the lysine 107 position causes gross chromosomal rearrangements. This lysine is located where two PCNA molecules ...
Cell & Microbiology
Jul 22, 2021
0
12
Scientists have waited months for access to highly accurate protein structure prediction since DeepMind presented remarkable progress in this area at the 2020 Critical Assessment of Structure Prediction, or CASP14, conference. ...
Molecular & Computational biology
Jul 15, 2021
0
5576
The principle that form follows function does not only apply to design and architecture. It also applies to biology. Every organism is a universe that lives thanks to the activities of tens of thousands of nanomachines, whose ...
Molecular & Computational biology
Jul 7, 2021
0
10
For the first time in the UAE, researchers at NYU Abu Dhabi have used nuclear magnetic resonance techniques to determine the structure of a specific nanobody, Nb23, potentially leading to a better understanding of how this ...
Biochemistry
Jul 2, 2021
0
9
An international team that includes researchers at TU Darmstadt has gained new insights into the protein structure and function of the ion channels that control the heartbeat. The results have now been published in the journal ...
Biotechnology
Jul 1, 2021
0
2
Bristle worms are found almost everywhere in seawater, they have populated the oceans for hundreds of millions of years. Nevertheless, some of their special features have only now been deciphered: Their jaws are made of remarkably ...
Plants & Animals
Jun 9, 2021
0
3
Scientists at Leipzig University, in collaboration with colleagues from Germany and England, have succeeded in reversibly slowing down cellular processes. A team of biophysicists led by Professor Josef Alfons Käs and Dr ...
Biochemistry
Jun 4, 2021
0
40
Polypharmacology—the ability of a drug to affect more than one protein—should be studied early in the drug discovery pathway, and constantly monitored as the chemical structure is optimized in the design of the clinical ...
Biochemistry
Jun 2, 2021
0
6
In a recent study, Australian scientists used an original approach to resolve the 3D structure of flaviviruses with an unprecedented level of detail, identifying small molecules known as 'pocket factors' as new therapeutic ...
Molecular & Computational biology
Jun 1, 2021
0
12
