Study shows protein hydrophobic parts do not hate water

Proteins are the workers, messengers, managers, and directors of nearly all inter- and intra-cellular functions in our body. So, all advances in biology, pharmaceuticals, and related fields hinge on having a fundamental understanding ...

Better in pairs: Proteins can help one another bind to DNA

Scientists from Tokyo Metropolitan University have uncovered a unique mechanism where two transcription factors stabilize each other's binding to DNA in fission yeast. They found that Atf1 and Rst2 help each other stably ...

AI algorithm solves structural biology challenges

Determining the 3-D shapes of biological molecules is one of the hardest problems in modern biology and medical discovery. Companies and research institutions often spend millions of dollars to determine a molecular structure—and ...

Appearance of cystic fibrosis at the molecular scale

Despite remarkable medical advances over the last years, cystic fibrosis remains the most prevalent lethal genetic disease. It is due to mutations in the CFTR protein which is normally required to maintain proper fluid balances ...

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