Researchers identify the source of asymmetry in RNA-DNA hybrids

A study headed by the Institute for Research in Biomedicine (IRB Barcelona) and published in the journal CHEM furthers the understanding of the asymmetry between nucleic acid hybrids. This advance may make a significant contribution ...

Anticancer mechanism revealed in yeast experiments

Much like shoelaces or dangly necklaces, DNA strands can tangle up in unruly knots. Specialized enzymes keep DNA organized when cells divide, so the cells split smoothly and don't get stuck. But in tumor cells, this failsafe ...

Trying to understand cells' interior design

How do you imagine the interior of our cells? Often compared to tiny factories, cells found smart and sophisticated ways to organize their interiors. Most biological processes require cells to bring together structures such ...

Math shows how DNA twists, turns and unzips

If you've ever seen a picture of a DNA molecule, you probably saw it in its famous B-form: two strands coiling around each other in a right-handed fashion to form a double helix. But did you know that DNA can change its shape?

The long and the short of DNA replication

The process of copying DNA is complex choreography that requires rapid speeds and pin-point precision. Discovering the intricate details of this process could identify new ways to target diseases, such as cancer, and KAUST ...

Programming synthetic molecular codes to turn genes 'on'

A team of researchers in Japan developed a synthetic molecular code to script gene activation. The process, described in the Journal of the American Chemical Society, could lead to future gene-based therapies for a wide array ...

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