Study characterizes key molecular tool in DNA repair enzymes
New research has revealed the function of a widely shared enzyme component, the Zf-GRF domain, as a critical molecular tool necessary for manipulating DNA during repair processes.
New research has revealed the function of a widely shared enzyme component, the Zf-GRF domain, as a critical molecular tool necessary for manipulating DNA during repair processes.
Cell & Microbiology
Jan 7, 2017
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26
For years, scientists have puzzled over what prompts the intertwined double-helix DNA to open its two strands and then start replication. Knowing this could be the key to understanding how organisms - from healthy cells to ...
Cell & Microbiology
Dec 13, 2016
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25
The base pairs found in DNA are key to its ability to store protein-coding information, but they also give the molecule useful structural properties. Getting two complementary strands of DNA to zip up into a double helix ...
Bio & Medicine
Nov 18, 2016
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759
Tinier than the AIDS virus—that is currently the circumference of the smallest transistors. The industry has shrunk the central elements of their computer chips to fourteen nanometers in the last sixty years. Conventional ...
Nanophysics
Nov 9, 2016
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4598
Scientists from the University of Basel have succeeded in organizing spherical compartments into clusters mimicking the way natural organelles would create complex structures. They managed to connect the synthetic compartments ...
Bio & Medicine
Nov 2, 2016
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13
A group coordinated by SISSA Trieste has built a 3-D computer model of the human genome. The shape of DNA (and its sequence) affects biological processes and is crucial for understanding its function. The study has provided ...
Biotechnology
Oct 27, 2016
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28
Researchers from the National Institute of Standards and Technology (NIST) and collaborators have proposed a design for the first DNA sequencer based on an electronic nanosensor that can detect tiny motions as small as a ...
Nanophysics
Sep 28, 2016
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13
Scientists from the University of Sussex have discovered how an enzyme, known as PARP3, helps to accelerate the repair of DNA.
Cell & Microbiology
Sep 5, 2016
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69
CRISPR-Cas9 is the go-to technique for knocking out genes in human cell lines to discover what the genes do, but the efficiency with which it disables genes can vary immensely.
Biotechnology
Aug 17, 2016
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172
It isn't often that a graduate student makes a spectacular technical leap in his field, or invents a process that can have a significant impact on a real-world problem. Di Liu did both.
Biochemistry
Aug 12, 2016
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36