Our proteome is much bigger than our genome because one gene produces several variants of proteins called protein isoforms, whose disbalance is implicated in many diseases. A new bioengineered reporter system developed at ...
Cell & Microbiology
Jun 4, 2021
0
12
RNA is the central tenet of molecular biology, the stepping-stone between DNA and proteins.
Biotechnology
Feb 4, 2021
0
572
Around 1 billion people on the planet are infected with parasitic helminths, round worms that live in soil and colonize human guts through dirty water. The helminths owe their ability to survive in the low oxygen environment ...
Molecular & Computational biology
Aug 4, 2020
0
17
Single-cell RNA sequencing (scRNA-seq) has revolutionized the ability to characterize cell types and their gene expression programs in organisms and tissues. Although great improvements in cellular throughput have been made, ...
Biotechnology
May 7, 2020
0
37
A research team at Children's Hospital of Philadelphia (CHOP) has developed an innovative computational tool offering researchers an efficient method for detecting the different ways RNA is pieced together (spliced) when ...
Molecular & Computational biology
Mar 25, 2019
0
204
A new University of Colorado Boulder-led study sheds light on the genetic mechanisms that allowed sunflowers to undergo a relatively rapid evolutionary transition from wild to domesticated in just over 5,000 years.
Evolution
Jun 11, 2018
0
11
A protein that plays an important role in embryonic development and nervous system wiring in humans appears to have been borrowed from bacteria. In a study published April 19, 2018, in Cell, scientists from the University ...
Cell & Microbiology
Apr 19, 2018
0
31
UCLA researchers have solved the high-resolution structure of a massive cellular machine, the spliceosome, filling the last major gap in our understanding of the RNA splicing process that was previously unclear.
Biochemistry
Nov 17, 2017
0
8
A research project that began 20 years ago with an interest in how lithium treats mood disorders has yielded insights into the progression of blood cancers such as leukemia. The research, which centers on a protein called ...
Biochemistry
Oct 31, 2017
0
25
Researchers from Princeton University and the National Institute of Environmental Health Sciences have discovered how a fruit fly protein binds and regulates two different types of RNA target sequence. The study, which will ...
Cell & Microbiology
Apr 4, 2017
0
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