What happens to gene transcription during DNA damage?

It's well known that when the DNA in a cell is damaged, the cell responds by activating specific genes that help defend the integrity of its genome. But less well studied is the fact that the cell actually shuts down the ...

Scientists find new roles for old RNAs

An international team of researchers has discovered unexpected functions of small nucleolar RNAs (snoRNAs) that explains the cause of some diseases. The research, led by Prof. Stefan Stamm from the University of Kentucky ...

Researchers illuminate 'dark side' of the transcriptome

A new way of mapping the "transcriptome"—the collection of RNA read-outs that are expressed by a cell's active genes—has been devised by researchers from the Perelman School of Medicine at the University of Pennsylvania. ...

Un-junking junk DNA

A study led by researchers at the University of California, San Diego School of Medicine shines a new light on molecular tools our cells use to govern regulated gene expression. The study was published on line in advance ...

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