Fly dreams and the boundaries of evolutionary science

In 2002, Secretary of state Donald Rumsfeld made a statement regarding weapons of mass destruction that today is still well known. He famously parsed the evidence (or lack thereof) into "known knowns, known unknowns, and ...

Determining the tempo of evolution across species

Scientists from Denmark and China have estimated germline mutation rates across vertebrates by sequencing and comparing genetic samples from 151 mother, father, and offspring trios from 68 species of mammals, fishes, birds ...

Mutations across animal kingdom shed new light on aging

The first study to compare the accumulation of mutations across many animal species has shed new light on decades-old questions about the role of these genetic changes in aging and cancer. Researchers from the Wellcome Sanger ...

New study paves the way for precision drugs to treat blood cancers

The Janus kinase 2 (JAK2) protein mediates signaling from several cytokine receptors in the regulation of hematopoiesis and immune responses. Somatic mutations in human JAK2 lead to constitutive activation and cytokine-independent ...

A NICER approach to genome editing

The gene editing technique CRISPR/Cas9 has allowed researchers to make precise and impactful changes to an organism's DNA to fix mutations that cause genetic disease. However, the CRISPR/Cas9 method can also result in unintended ...

page 1 from 3