Scientists know that age and weight are risk factors in the development of cancer. That should mean that whales, which include some of the largest and longest-lived animals on Earth, have an outsized risk of developing cancer.
Molecular & Computational biology
May 9, 2019
1
266
Mutation rates are proposed to be a pragmatic balance struck between the harmful effects of mutations and the costs of suppressing them; this hypothesis predicts that longer-lived body parts and those that contribute to the ...
Biotechnology
Apr 9, 2019
0
33
In mammals, females have a limited supply of oocytes. Oocytes have a unique epigenome with approximately half the DNA methylation of sperm, and the most terminally differentiated somatic cells. Until recently, regulators ...
Biotechnology
Nov 29, 2018
0
55
Key insights into how sperm and egg cells are formed have been discovered by scientists, shedding light on the earliest stages of their development.
Biotechnology
Oct 3, 2018
0
95
Since their discovery in 2006, induced pluripotent stem cells are a glimmer of hope for many diseases. But further research of the complex regulation of pluripotent stem cell identity is unexpectedly difficult. A team of ...
Cell & Microbiology
Nov 13, 2017
0
155
A team of researchers, led by a plant cell biologist at the University of California, Riverside, has for the first time identified a small RNA species and its target gene that together regulate female germline formation in ...
Biotechnology
May 25, 2017
0
8
In various vertebrate species, including fish, amphibians, reptiles, birds and mammals, the DMRT1 gene is a master sex regulator, working to develop and maintain 'maleness' -either the sex cells (or germline) into testis ...
Evolution
Dec 6, 2016
0
351
To date, it has been assumed that the differentiation of stem cells depends on the environment they are embedded in. A research group at the University of Basel now describes for the first time a mechanism by which hippocampal ...
Cell & Microbiology
Aug 18, 2016
0
59
In a new Cell Reports paper, a team led by John P. Cooke, M.D., Ph.D., of the Houston Methodist Research Institute, has identified and characterized a biological factor critical to the transformation of adult somatic cells ...
Cell & Microbiology
Apr 21, 2016
0
62
In female mammals, one of the two X chromosomes is inactivated. Thanks to research using special stem cells, geneticists at ETH Zurich have been able to provide detailed insight into the molecular mechanism behind this inactivation ...
Biotechnology
Aug 10, 2015
1
51
