New approach enables faster characterization of CRISPR immune systems

For many diseases, the tools of medicine are reaching their limits. CRISPR technologies open new avenues for diagnostics and therapies, although the natural source of CRISPR remains largely untapped. Scientists from the Helmholtz ...

Probing how proteins pair up inside cells

Despite its minute size, a single cell contains billions of molecules that bustle around and bind to one another, carrying out vital functions. The human genome encodes about 20,000 proteins, most of which interact with partner ...

Modeling how cells choose their fates

It may seem hard to believe, but each one of us began as a single cell that proliferated into the trillions of cells that make up our bodies. Though each of our cells has the exact same genetic information, each also performs ...

Nested nanowells speed single cell studies

Researchers tracking the behavior of cancerous tumor cells have a new tool in their arsenal that can process 10 times the number of cells in one day. A new nested nanoPOTS chip, developed at Pacific Northwest National Laboratory ...

Scanning a single protein, one amino acid at a time

Using nanopore DNA sequencing technology, researchers from TU Delft and the University of Illinois have managed to scan a single protein. By slowly moving a linearized protein through a tiny nanopore, one amino acid at the ...

Fixing protein production errors lengthens lifespan

Reducing naturally occurring errors in protein synthesis (production) improves both health and lifespan, finds a new study in simple model organisms led by researchers at UCL and MRC London Institute of Medical Sciences.

Appearance of cystic fibrosis at the molecular scale

Despite remarkable medical advances over the last years, cystic fibrosis remains the most prevalent lethal genetic disease. It is due to mutations in the CFTR protein which is normally required to maintain proper fluid balances ...

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