The front line of the human immune system is made up of T-cells: white blood cells that circulate in the body and scan for foreign invaders and infections. If a T-cell surface receptor detects a threat during its surveillance, ...
Cell & Microbiology
Apr 11, 2016
0
659
Majority of human Src homology 2 domains not only bind to proteins, but also interact with membrane lipids with high affinity and specificity. The SH2 domain-containing proteins play important roles in various physiological ...
Cell & Microbiology
Mar 28, 2016
0
6
New research has revealed that a plant protein known to detect growth-promoting compounds in smoke from burning vegetation has a much older and broader role: recognising initial signals sent from the beneficial soil fungi ...
Biotechnology
Dec 17, 2015
0
364
A biomedical breakthrough published today in the journal Nature reveals never-before-seen details of the human body's cellular switchboard that regulates sensory and hormonal responses. The work is based on an X-ray laser ...
General Physics
Jul 22, 2015
0
130
In biology and medicine, we often need to detect biological molecules. For example, in cancer diagnostics, doctors need quick and reliable ways of knowing if tumor cells are present in the patient's body. Although such detection ...
Biochemistry
Jul 22, 2015
0
30
Insight into the regulation of cell skeleton structure has come from a study conducted by A*STAR researchers. The work, which solved a protein structure that has eluded scientists for 20 years, should lead to further insights ...
Cell & Microbiology
Jun 24, 2015
0
19
In order for newly-produced secretory or membrane proteins to find their final destination, the proteins have signal-sequences connected to themselves as a form of address tag. Furthermore, they use a particle guiding them ...
Cell & Microbiology
Jun 16, 2015
0
7
In proof-of-concept experiments, researchers at University of California, San Diego School of Medicine demonstrate the ability to tune medically relevant cell behaviors by manipulating a key hub in cell communication networks. ...
Cell & Microbiology
May 1, 2015
0
1083
Most animals have a dorso-ventral (back-to-belly) body axis, which determines for instance the localized position of the central nervous system, dorsal in humans, ventral in insects. Surprisingly, despite enormous morphological ...
Cell & Microbiology
Mar 18, 2015
0
5
Just as human relationships are a two-way street, fusion between cells requires two active partners: one to send protrusions into its neighbor, and one to hold its ground and help complete the process. Researchers have now ...
Cell & Microbiology
Feb 12, 2015
0
16
