Protein structure reveals how cells regulate their skeletons

Insight into the regulation of cell skeleton structure has come from a study conducted by A*STAR researchers. The work, which solved a protein structure that has eluded scientists for 20 years, should lead to further insights ...

Structural data reveals new mechanism behind protein transport

In order for newly-produced secretory or membrane proteins to find their final destination, the proteins have signal-sequences connected to themselves as a form of address tag. Furthermore, they use a particle guiding them ...

Evolution of the back-to-belly axis

Most animals have a dorso-ventral (back-to-belly) body axis, which determines for instance the localized position of the central nervous system, dorsal in humans, ventral in insects. Surprisingly, despite enormous morphological ...

An "anchor" that keeps proteins together

All organisms react to different external and internal stimuli: if, for example, the hyphae fungus Sordaria macrospora is supplied with food, it produces fruiting bodies as part of its oestrous cycle. To initiate this reaction, ...

Detecting tumor markers easily

Blood is just teeming with proteins. It's not easy there to identify specialized tumor markers indicating the presence of cancer. A new method now enables diagnostics to be carried out in a single step. Scientists will present ...

Breaking up the superbugs' party

The fight against antibiotic-resistant superbugs has taken a step forward thanks to a new discovery by scientists at The University of Nottingham.

Salk scientists add new bond to protein engineering toolbox

Proteins are the workhorses of cells, adopting conformations that allow them to set off chemical reactions, send signals and transport materials. But when a scientist is designing a new drug, trying to visualize the processes ...

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