A protein that pulls the brake on nerve growth

During embryonic development, nerve cells form long, thin extensions that wire up the complex network of the brain. Scientists from the German Center for Neurodegenerative Diseases (DZNE) in Bonn have now identified a protein ...

How cells protect themselves from mitochondrial defects

Cells need powerhouses known as mitochondria to utilize the energy stored in our food. Most of the proteins required for this powerhouse function are encoded in the nucleus and transported into the mitochondria after they ...

Mitochondrial unfolded protein response signals imminent danger

Misfolded proteins must be promptly eliminated as they can form toxic aggregates in cells. LMU biologists have studied how this process is triggered in mitochondria and identified a general alarm signal that activates it.

Lighting up proteins with Immuno-SABER

To better understand how tissues and organs develop, fail to function, and regenerate over time, researchers would like to visualize their constituent cells' repertoires of molecules within 3-D space. Ambitious efforts like ...

How plants can tell time even without a brain

Anyone who has traveled across multiple time zones and suffered jet lag will understand just how powerful our biological clocks are. In fact, every cell in the human body has its own molecular clock, which is capable of generating ...

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