At the center of every cell, highly organized chromatin encodes the program of life with just one set of genes. This is possible because different genes are activated at different stages of life while remaining silent otherwise. ...
Cell & Microbiology
May 31, 2022
0
38
Chromosomal instability is a feature of solid tumors such as carcinoma. Likewise, cellular senescence is a process that is highly related to cellular aging and its link to cancer is becoming increasingly clear. Scientists ...
Evolution
Jul 6, 2021
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16
Heat shock (or stress) is a well-known factor of cell stress, though its delayed effects remain largely unknown. According to two articles by Russian scientists —a 2015 article in Nucleic Acids Research and a February article ...
Cell & Microbiology
Mar 25, 2016
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7
Researchers at the Universitat Pompeu Fabra (UPF), ICREA, CIBERNED, CNIC and Altos Labs, among other national and international collaborators, have characterized how damaged cells (senescent cells) that inevitably arise after ...
Cell & Microbiology
Dec 21, 2022
0
20
Aging and age-related disorders pose a complex challenge to the biomedical research community. To better understand how senescence is regulated is of high significance to promote healthy aging and treat age-associated disorders. ...
Cell & Microbiology
Jul 18, 2022
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86
In a warming climate, spring keeps getting earlier. But the timing of leaf fall in autumn has been more of a mystery. For the first time, a study by researchers including biologist Susanne Renner in Arts & Sciences at Washington ...
Plants & Animals
Jul 7, 2023
0
147
Research carried out at the Institute of Molecular Biology and Biotechnology (IMBB) of FORTH, provides evidence that persistent DNA damage triggers an exosome-based, metabolic reprogramming that leads to chronic inflammation ...
Cell & Microbiology
Nov 26, 2021
0
154
Cell senescence is a state of permanent cell cycle arrest that was initially defined for cells grown in cell culture. It plays a key role in age-associated organ dysfunction and age-related diseases such as cancer, but the ...
Cell & Microbiology
Oct 7, 2020
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9
Researchers from Kumamoto University, Japan have proposed that cellular senescence variations during the aging process could lead to control of health and onset of age-related diseases. Based on the characteristics of the ...
Cell & Microbiology
Oct 26, 2020
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5
It has been widely acknowledged for a long time that mitochondrion is the main source of reactive oxygen species (ROS). The role of the endoplasmic reticulum (ER)-generated ROS has been less extensively studied. It has been ...
Cell & Microbiology
Aug 4, 2023
0
1
