Before messenger RNA molecules can be translated into amino acids and eventually functional proteins, the primary gene transcripts must be spliced to remove non-coding sequences. Misato Ohtani from the RIKEN Center for Sustainable ...
Cell & Microbiology
Aug 9, 2013
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A little-studied factor known as the Little Elongation Complex (LEC) plays a critical and previously unknown role in the transcription of small nuclear RNAs (snRNA), according to a new study led by scientists at the Stowers ...
Cell & Microbiology
Aug 8, 2013
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Like an impossibly twisted telephone cord, DNA, the molecule that encodes genetic information, also often finds itself twisted into coils. This twisting, called supercoiling, is caused by enzymes that travel along DNA's helical ...
Cell & Microbiology
Jun 28, 2013
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You say tomato, I say comparative transcriptomics. Researchers in the U.S., Europe and Japan have produced the first comparison of both the DNA sequences and which genes are active, or being transcribed, between the domestic ...
Biotechnology
Jun 26, 2013
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Small molecules of RNA (tens to hundreds of nucleotides in length) play a key regulatory role in bacteria. Due to their small size, directly measuring the number of small RNA (sRNA) present in a single bacterium has proven ...
Analytical Chemistry
Jun 18, 2013
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A team led by scientists at The Scripps Research Institute (TSRI) has found how to boost or inhibit a gene-silencing mechanism that normally serves as a major controller of cells' activities. The discovery could lead to a ...
Cell & Microbiology
May 9, 2013
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An international research team in including Christian Schlötterer and Alistair McGregor of the Vetmeduni Vienna has discovered a completely new mechanism by which evolution can change the appearance of an organism. The ...
Biotechnology
Apr 19, 2013
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Many different tissues and organs form from pluripotent stem cells during embryonic development. To date it had been known that these processes are controlled by transcription factors for specific tissues. Scientists from ...
Cell & Microbiology
Jan 29, 2013
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When genes were first discovered, the canonical view was that each gene encodes a unique protein. However, biologists later found that segments of genes can be combined in different ways, giving rise to many different proteins.
Evolution
Dec 21, 2012
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Histones—proteins that package DNA—affect cell function differently than previously assumed: the cell doesn't need the histone H3.3 to read genes. Molecular biologists from the University of Zurich demonstrate that fruit ...
Cell & Microbiology
Nov 13, 2012
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