Before DNA can be transcribed into RNA, an early step in turning the genetic template into protein, the nucleus must first assemble a molecular machine called the pre-initiation complex (PIC), capable of unzipping the double ...
Cell & Microbiology
Dec 2, 2014
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Case Western Reserve School of Medicine scientists have made an extraordinary double discovery. First, they have identified thousands of novel long non-coding ribonucleic acid (lncRNA) transcripts. Second, they have learned ...
Cell & Microbiology
Jun 23, 2014
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(Phys.org) —A team of researchers working at the University of Tokyo has at long last uncovered the mysterious mechanism by which gender is determined in the silkworm (and other lepidoterans). In their paper published in ...
DNA is the molecule that encodes the genetic instructions enabling a cell to produce the thousands of proteins it typically needs. The linear sequence of the A, T, C, and G bases in what is called coding DNA determines the ...
Biotechnology
Mar 31, 2014
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A presentation at Genetics Society of America's Drosophila Research Conference builds the case that de novo genes derived from ancestral non-coding DNA can spread through a species.
Biotechnology
Mar 26, 2014
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Embryonic stem cells (ESCs) retain their ability to self-renew indefinitely thanks to a number of proteins known as pluripotency factors. These factors must be modified at the RNA level before they are turned into proteins ...
Cell & Microbiology
Jan 29, 2014
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(Phys.org) —Bioengineers from the University of California, San Diego have created a new method for analyzing RNA transcripts from samples of 50 to 100 cells. The approach could be used to develop inexpensive and rapid ...
Biotechnology
Oct 24, 2013
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Scientists at A*STAR's Genome Institute of Singapore (GIS), in collaboration with their counterparts from Canada, Hong Kong and US, have discovered a protein mediator SON plays a critical role in the health and proper functioning ...
Cell & Microbiology
Sep 9, 2013
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MIT researchers have shown that they can turn genes on or off inside yeast and human cells by controlling when DNA is copied into messenger RNA—an advance that could allow scientists to better understand the function of ...
Biotechnology
Sep 3, 2013
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A study investigating the function of the recently discovered enhancer RNA molecules may open new avenues for gene therapy. According to the study researchers, altering the production and function of these molecules could ...
Cell & Microbiology
Aug 13, 2013
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