Researchers uncover mechanism behind DNA damage control

DNA damage is occurring in our cells all the time due to external agents, such as exposure to sun, or internal agents, like reactive oxygen species. To detect and repair DNA lesions, cells have evolved DNA damage response. ...

Keeping chromosomes in check: A new role for heterochromatin

Although many people are aware that chromosomal damage and shortening contribute to the aging process, understanding how chromosomal defects occur is about more than just finding a way to turn back the clock. Large changes ...

DNA origami full of potent anticancer agents

One of the most successful techniques to combat multidrug resistance in cancer cells is the downregulation of those genes responsible for drug resistance. Chinese scientists have now developed a nanoplatform that selectively ...

Regulating gene transcription using light

Researchers led by Mustafa Khammash have developed a new method that uses blue light to control the transcription of DNA into RNA in single cells. The technology could also be used in tissue engineering and stem cell research.

Genetic transcription 'pause' is focus of NASA grant

DNA is a blueprint for cells to make proteins that allow those cells to function properly. To create the proteins, enzymes copy genetic codes from DNA strands and then transfer the instructions onto RNA in a process called ...

Missing link found between pathways involved in cell development

A new mechanism that coordinates human development in response to signals from outside the cell has been discovered by researchers at the Wellcome Sanger Institute and the Wellcome - MRC Cambridge Stem Cell Institute. Reported ...

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