The Hirohide Saito Laboratory has developed cyclic RNA switches that can control gene expression in a cell type-specific manner using miRNAs and RNA-binding proteins and has successfully constructed an artificial gene circuit ...
Cell & Microbiology
Feb 16, 2023
0
2
Genetic information encoded in genomic DNA is transcribed to mRNAs and then the codons on mRNA are decoded by transfer RNAs (tRNAs) during protein synthesis. tRNAs deliver amino acids to ribosomes and proteins are synthesized ...
Biochemistry
Dec 27, 2022
0
68
Studying the role of mitochondria—the specialized structures within cells responsible for energy production—in metabolic diseases has been difficult because of a lack of animal models with the necessary mitochondrial ...
Cell & Microbiology
Aug 25, 2022
0
4
A group of Skoltech researchers under Dr. Olga Sergeeva's supervision studied the functions of a long non-coding RNA, which is "read" from the genome, but does not carry the information about protein structure. In experiments ...
Cell & Microbiology
Jul 7, 2022
0
5
The zebrafish is an important model organism in biology. Humans and zebrafish share 70 percent of their genes, and more than 80 percent of human genes associated with disease are known to have a zebrafish counterpart. Additionally, ...
Molecular & Computational biology
Oct 8, 2019
0
10
One of the most fundamental unexplained questions in modern science is how life began. Scientists generally believe that simple molecules present in early planetary environments were converted to more complex ones that could ...
Space Exploration
Nov 30, 2018
0
9
Ribonucleic acid (RNA) is, along with DNA and protein, one of the three primary biological macromolecules and was probably the first to arise in early life forms. In the "RNA world" hypothesis, RNA is able to support life ...
Biochemistry
Nov 6, 2018
0
10
Think of life as a house: if DNA molecules are blueprints, then messenger RNAs (mRNAs) are orders, describing the required parts (proteins) and when they should arrive. But putting in many orders doesn't always mean you'll ...
Biochemistry
May 3, 2017
0
7
Protein synthesis is programmed by messenger RNAs, and when enough of a given protein has been made, the mRNAs that encode it are destroyed. LMU researchers have now shown that protein synthesis and mRNA degradation are structurally ...
Cell & Microbiology
Jan 26, 2017
0
8
The ability to dispose of proteins that are either aberrant or (in the worst case) toxic is fundamental to a cell's survival. Researchers from Charité - Universitätsmedizin Berlin have been able to demonstrate the manner ...
Cell & Microbiology
Jan 19, 2017
0
5
