Scientists have found a single protein—Ptbp2—controls a network of over 200 genes central to how developing sperm move and communicate. The protein works by regulating how RNA is processed during each stage of sperm development.
Cell & Microbiology
Jul 10, 2017
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3
With over 75 million baby boomers in the U.S. alone, age-related diseases are a major concern in the health care system. The connection between aging and cancer has become a pillar in medicine: we know that as we age, our ...
Biotechnology
Oct 7, 2016
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20
While the number of coding genes that produce proteins in humans has dwindled to 20,000 in recent years, scientists think that the dimensions of the proteome could be larger. This diversity of proteins has become one of the ...
Biochemistry
Oct 4, 2016
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If you imagine a cell as a house, protein production can be a fairly relatable engineering feat. A master blueprint (DNA) holds all the information about what goes where. If you just want to build a door (protein), you only ...
Cell & Microbiology
Feb 25, 2016
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9
Embryonic stem cells (ESCs) retain their ability to self-renew indefinitely thanks to a number of proteins known as pluripotency factors. These factors must be modified at the RNA level before they are turned into proteins ...
Cell & Microbiology
Jan 29, 2014
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0
Certain diseases such as cystic fibrosis and muscular dystrophy are linked to genetic mutations that damage the important biological process of rearranging gene sequences in pre-messenger RNA, a procedure called RNA splicing.
Cell & Microbiology
Sep 26, 2013
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2
Numerous biological processes depend on molecules called lariat RNAs (LaRNAs). These lasso-shaped structures form in the cell during RNA splicing. During this process, transcribed RNA strands convert to messenger RNA before ...
Biochemistry
May 24, 2012
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0
Researchers report this month that MALAT1, a long non-coding RNA that is implicated in certain cancers, regulates pre-mRNA splicing - a critical step in the earliest stage of protein production. Their study appears in the ...
Cell & Microbiology
Sep 23, 2010
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0
Researchers in human genetics have long known that expansions of GAA repeats - resulting in this nucleotide triplet repeating hundreds or thousands of times - cause the most common hereditary neurological disorder known as ...
Cell & Microbiology
Jul 9, 2009
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0
The central nervous system, which comprises the brain and spinal cord, is constructed by the proper proliferation of neural progenitor cells and their differentiation into neurons and glial cells. The transcription factor ...
Cell & Microbiology
Mar 15, 2022
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