Researchers have provided new insight on the mechanism underlying the control of gene expression in all living organisms, according to a study published today in eLife.
Cell & Microbiology
Jan 8, 2019
0
100
Damage to DNA is a constant threat to cellular life, and so it is constantly monitored and detected by a family of enzymes called RNA polymerases, resulting in subsequent repair to maintain genome integrity. In a paper published ...
Biotechnology
Aug 22, 2018
0
57
In eukaryotic cells, linear genetic DNA wraps around histones to form stable nucleosomes that further assemble to form chromatins. Nucleosomes represent big barriers to the transcription machine RNA polymerase.
Cell & Microbiology
Jul 23, 2018
0
11
Scientists have shed light on DNA 'melting' – a crucial process fundamental to all life.
Cell & Microbiology
Jun 22, 2018
0
75
When cells grow and divide to ensure a biological function—such as a properly working organ—DNA must be unwound from its typical tightly packed form and copied into RNA to create proteins. When this process goes awry—if ...
Cell & Microbiology
Jun 21, 2018
0
25
This year's unexpectedly aggressive flu season reminds everyone that although the flu vaccine can reduce the number of people who contract the virus, it is still not 100 percent effective. Researchers report that a tweak ...
Biochemistry
Mar 19, 2018
0
177
Using an innovative crystallization technique for studying three-dimensional structures of gene transcription machinery, an international team of researchers, led by scientists at Penn State, has revealed new insights into ...
Cell & Microbiology
Feb 22, 2018
0
101
Pioneering new research could offer a fascinating new insight into how genomic information is read.
Biotechnology
Feb 12, 2018
2
30
Using a molecule designed to overcome a roadblock formed by a common type of genetic flaw, researchers at the University of Wisconsin-Madison have made progress towards novel molecular treatments for Friedreich's ataxia—a ...
Biotechnology
Nov 30, 2017
0
80
A recently described variety of RNA closely associated with gene expression was found to be largely cell-type specific, raising the possibility this variety of RNA sequences may be able to be used as a marker in stem cell ...
Cell & Microbiology
Aug 30, 2017
0
28
