High-resolution crystal structure reveals a new pathway for RNA during a nontraditional form of transcription—the process by which RNA is produced from a DNA template. Caught during the act of reiterative transcription, ...
Cell & Microbiology
Aug 22, 2017
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6
A new study describes how head-on collisions between protein machines on chromosomes can disrupt DNA replication and boost the rate of gene mutations that help bacteria survive hostile environments, resist antibiotics, and ...
Cell & Microbiology
Aug 15, 2017
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8
A novel approach developed at the Friedrich Miescher Institute for Biomedical Research (FMI) has allowed scientists in Dirk Schübeler's group to dissect and quantify the individual steps of transcription initiation. Unexpectedly, ...
Cell & Microbiology
Jul 26, 2017
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15
Scientists from Rutgers University-New Brunswick, the biotechnology company NAICONS Srl., and elsewhere have discovered a new antibiotic effective against drug-resistant bacteria: pseudouridimycin. The new antibiotic is produced ...
Cell & Microbiology
Jun 15, 2017
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672
There are many processes that take place in cells that are essential for life. Two of these, transcription and translation, allow the genetic information stored in DNA to be deciphered into the proteins that form all living ...
Cell & Microbiology
Apr 13, 2017
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38
With the first detailed analysis of a cellular component from a close relative of the pathogen that causes tuberculosis, Rockefeller scientists are suggesting strategies for new drugs to curb this growing health problem. ...
Biochemistry
Feb 3, 2017
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422
Some cells just don't get the respect they deserve. In fact, most cells don't. Over 99 percent of the innumerable cells on our planet exist in a state of quiescence. Pick up a handful of soil: it contains thousands of microorganisms, ...
Cell & Microbiology
Nov 9, 2016
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299
A new study by researchers at Princeton University suggests that sporadic bursts of gene activity may be important features of genetic regulation rather than just occasional mishaps. The researchers found that snippets of ...
Cell & Microbiology
Jul 19, 2016
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7
Rutgers University scientists have discovered the three-dimensional structure of a gene-specific transcription activation complex, providing the first structural and mechanistic description of the process cells use to turn ...
Cell & Microbiology
Jun 9, 2016
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10
Gene transcription is the process by which DNA is copied and synthesized as messenger RNA (mRNA)—which delivers its genetic blueprints to the cell's protein-making machinery.
Cell & Microbiology
May 26, 2016
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