Genomes are routinely subjected to DNA damage. But most cells have DNA repair systems that enforce genome stability and, ideally, prevent diseases like cancer. The trouble gets serious when these systems break down. When ...
Molecular & Computational biology
Sep 16, 2020
0
44
Chemical reactions driven by the geological conditions on the early Earth might have led to the prebiotic evolution of self-replicating molecules. Scientists at Ludwig-Maximilians Universitaet (LMU) in Munich now report on ...
Biochemistry
Aug 7, 2020
1
397
In your cells, it's almost always spring. Or at least springy.
Molecular & Computational biology
Jan 30, 2020
0
47
The quest to better understand how genomic information is read has taken a new step forward, thanks to pioneering new research.
Molecular & Computational biology
Dec 6, 2019
0
69
Scientists at the Gladstone Institutes have made a key observation about one of the most fundamental biological processes: gene transcription.
Molecular & Computational biology
May 2, 2019
0
126
A protein complex that is involved in nearly every step in the regulatory control of gene expression in cells has now been shown also to play a key role in clearing potential traffic jams in the production of RNA.
Molecular & Computational biology
Apr 5, 2019
0
121
The message of life is encoded in our genomic DNA through transcription of messenger RNAs and translation of proteins to perform cellular functions. To ensure accurate transcription—a process that transcribes genomic DNA ...
Materials Science
Apr 3, 2019
0
81
Whether revealing a perpetrator with DNA evidence, diagnosing a pathogen, classifying a paleontological discovery, or determining paternity, the duplication of nucleic acids (amplification) is indispensable. In the journal ...
Biochemistry
Mar 12, 2019
1
115
Viruses depend on host cells for replication, but how does a virus induce its host to transcribe its own genetic information alongside that of the virus, thus producing daughter viruses? For decades, researchers have been ...
Cell & Microbiology
Mar 7, 2019
0
23
Researchers in Japan have discovered that the DNA inside human cells moves around less when its genes are active. The study, which will be published March 1 in the Journal of Cell Biology, suggests that RNA polymerase II ...
Cell & Microbiology
Mar 1, 2019
0
15
