One way of regulating protein levels in cells is to shorten the lifespan of messenger RNAs (mRNAs). These are intermediary molecules that are first copied from DNA in the cell's nucleus via a process called transcription ...
Cell & Microbiology
Jun 25, 2010
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Researchers at the Stanford University School of Medicine have identified a new group of proteins involved in determining the life span of laboratory roundworms. Blocking the expression of one member of the group can extend ...
Biotechnology
Jun 16, 2010
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(PhysOrg.com) -- A multi-institutional team of researchers and clinicians has published the first proof that a targeted nanoparticle can traffic into tumors, deliver double-stranded small interfering RNAs (siRNAs), and turn ...
Bio & Medicine
Apr 21, 2010
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A California Institute of Technology (Caltech)-led team of researchers and clinicians has published the first proof that a targeted nanoparticle -- used as an experimental therapeutic and injected directly into a patient's ...
Bio & Medicine
Mar 21, 2010
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Biologists at the University of Pennsylvania studying oocytes in mice, the immature egg cells necessary for sexual reproduction, have demonstrated an unusual behavior in microRNA, or miRNA, activity that may be the first ...
Cell & Microbiology
Feb 3, 2010
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A team of scientists at Cold Spring Harbor Laboratory (CSHL) has determined a hierarchical set of criteria that explain how the molecular precursors of gene-regulating small RNAs are sorted by the cellular machinery.
Cell & Microbiology
Jan 4, 2010
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Every high school biology student learns the basics of how genes are expressed: DNA, the cell’s master information keeper, is copied into messenger RNA, which carries protein-building instructions to the ribosome, the part ...
Cell & Microbiology
Nov 12, 2009
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(PhysOrg.com) -- Aided by a genomic map of the red flour beetle, Tribolium castaneum, Agricultural Research Service (ARS) and university scientists are plotting a kind of genetic sabotage on the pest’s basic life functions ...
Other
Nov 3, 2009
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In new papers appearing this month in Science and the Proceedings of the National Academy of Sciences, University of Illinois biochemistry professor Raven H. Huang and his colleagues describe the first RNA repair system to ...
Cell & Microbiology
Oct 12, 2009
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UCSF scientists have created a method of quickly identifying large numbers of the genetic material known as short hairpin RNA — also called shRNA - that turns genes on and off.
Cell & Microbiology
May 19, 2009
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