How does a mobile DNA sequence find its target?

To understand how transposable elements shape genomes, where they are maintained over generations, it is vital to discover the mechanisms behind their targeted integration. Researchers from the Laboratoire Pathologie et Virologie ...

Single cells seen in unprecedented detail

Researchers have developed a large-scale sequencing technique called Genome and Transcriptome Sequencing (G&T-seq) that reveals, simultaneously, the unique genome sequence of a single cell and the activity of genes within ...

Viral switches share a shape

A hinge in the RNA genome of the virus that causes hepatitis C works like a switch that can be flipped to prevent it from replicating in infected cells. Scientists have discovered that this shape is shared by several other ...

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