A molecular on/off switch for CRISPR

Picture bacteria and viruses locked in an arms race. For many bacteria, one line of defense against viral infection is a sophisticated RNA-guided "immune system" called CRISPR-Cas. At the center of this system is a surveillance ...

Scientists deconstruct one of the myths of biological innovation

While the number of coding genes that produce proteins in humans has dwindled to 20,000 in recent years, scientists think that the dimensions of the proteome could be larger. This diversity of proteins has become one of the ...

Analysis of dog genome will provide insight into human disease

An important model in studying human disease, the non-coding RNA of the canine genome is an essential starting point for evolutionary and biomedical studies—according to a new study led by The Genome Analysis Centre (TGAC).

A virus common among livestock depends on a micro-RNA to replicate

In the ongoing arms race between pathogenic viruses and the cells they infect, each side needs every advantage it can get. One way wily viruses can get a leg up is by subverting the microRNAs (miRNAs) of their host. These ...

Raw material for new genes

Every region of DNA codes for a gene. Well, not quite. Although an organism's genome contains some regions that are read and transcribed into RNA, many of those do not give rise to functional genes. Scientists at the Max ...

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