Protein synthesis is a finely tuned process in the cell by macromolecules known as ribosomes. Which regulators are responsible for controlling protein synthesis in the brain, and how do they exert their control on the ribosome? ...
Molecular & Computational biology
Dec 22, 2020
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5
Ribosomes are the machines in the cell that use instructions from mRNA to synthesize functional proteins. There are hundreds of thousands of ribosomes in each cell, and they mostly process their instructions faithfully. But ...
Cell & Microbiology
Dec 17, 2020
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15
Researchers at Karolinska Institutet characterize a GTPase involved in ribosome biogenesis in mitochondria. The study, published in Nucleic Acid Research, reveals new details of a complex process that enables mitochondria ...
Biotechnology
Dec 7, 2020
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13
Ribosomes synthesize all the proteins in cells. Studies mainly done on yeast have revealed much about how ribosomes are put together, but an Ludwig-Maximilians-Universitaet (LMU) in Munich team now reports that ribosome assembly ...
Cell & Microbiology
Nov 23, 2020
0
63
Maturation of the ribosome is a complex operation. Work by an LMU team now shows that the 90S precursor of the small 40S subunit undergoes a "molting" process, during which it progressively discards its outermost components.
Molecular & Computational biology
Sep 22, 2020
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24
Researchers at ETH Zurich and the University of Bern have discovered a mechanism by which the corona virus manipulates human cells to ensure its own replication. This knowledge will help to develop drugs and vaccines against ...
Cell & Microbiology
Sep 14, 2020
0
112
On the evolutionary tree, humans diverged from yeast roughly 1 billion years ago. By comparison, two seemingly similar species of bacteria, Escherichia coli and Bacillus subtilis, have been evolving apart for roughly twice ...
Molecular & Computational biology
Sep 3, 2020
1
75
ETH Zurich researchers can predict how tightly a cell's protein synthesis machinery will bind to RNA sequences—even when dealing with many billions of different RNA sequences. This binding plays a key role in determining ...
Molecular & Computational biology
Aug 27, 2020
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53
Researchers from Skoltech, Lomonosov Moscow State University and the Kharkevich Institute for Information Transmission Problems have studied the genomes of some 200 strains of bacteria to determine which proteins in the ribosome, ...
Evolution
Aug 11, 2020
1
0
When cells experience a high level of stress—for example, when they are exposed to too much UV light—ribosomes inside the cell collide and get into traffic jams. Now, Johns Hopkins scientists have found a protein that ...
Cell & Microbiology
Aug 5, 2020
0
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