(Phys.org)—There is a whole lot more to the textbook mitochondrial genome then once was thought. A case in point is a multifunctional peptide named humanin that is dual-encoded deep within 16S ribosomal RNA gene in the ...
Ribosomes, ancient molecular machines that produce proteins in cells, are required for cell growth in all organisms, accomplishing strikingly complex tasks with apparent ease. But defects in the assembly process and its regulation ...
Cell & Microbiology
Mar 16, 2015
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The ribosome is the protein-making "factory" within cells responsible for knitting together amino acids into polypeptide chains that form proteins.
Cell & Microbiology
Jan 22, 2015
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Since the discovery that DNA encodes genetic information, research on the evolution of life has focused on its genetic origins. Following this "genes-first" approach, Oxford University evolutionary biologist Richard Dawkins ...
Cell & Microbiology
Jan 7, 2015
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In order to infect a host cell and proliferate, some viruses, such as the hepatitis C virus, infiltrate the ribosomes, the molecular machines that assemble the proteins present in each of our cells. Viral proteins are thus ...
Cell & Microbiology
Dec 2, 2014
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Damage to DNA is an issue for all cells, particularly in cancer, where the mechanisms that repair damage typically fail. The same agents that damage DNA also damage its sister molecule messenger RNA (mRNA), which ferries ...
Cell & Microbiology
Nov 13, 2014
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High-resolution cryo-electron microscopy has now revealed in unprecedented detail the structural changes in the bacterial ribosome which results in resistance to the antibiotic erythromycin.
Cell & Microbiology
Oct 13, 2014
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Researchers at ETH Zurich are decoding the structure of the large ribosomal subunit of the mitochondria at an atomic level, thereby providing insight into the molecular architecture of this ribosome with implications for ...
Biochemistry
Oct 8, 2014
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The so-called central dogma of molecular biology—that DNA makes RNA which makes protein—has long provided a simplified explanation for how genetic information is deciphered and translated in living organisms.
Cell & Microbiology
Sep 15, 2014
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One challenge in killing off harmful bacteria is that many of them develop a resistance to antibiotics. Researchers at the University of Rochester are targeting the formation of the protein-making machinery in those cells ...
Cell & Microbiology
Sep 7, 2014
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