Scientists at the MRC-MBU in Cambridge, U.K., have discovered how a key transport protein, called the mitochondrial ADP/ATP carrier, transports adenosine triphosphate (ATP), the chemical fuel of the cell. This process is ...
A team of Florida State University researchers has unlocked a decades-old mystery about how a critical cellular process is regulated and what that could mean for the future study of genetics.
Cells have in place a number of mechanisms to protect the integrity of the genome, including processes that repair mistakes that may occur during DNA replication. The enzyme Dna2 participates in DNA repair, but little is ...
Scientists reveal how a 'molecular machine' in bacterial cells prevents fatal DNA twisting, which could be crucial in the development of new antibiotic treatments.
Understanding how and when cells divide is important to figuring out everything from how cancers grow to why some mammals are able to get so big. A new study of E. coli cell data, published November 7 in Science Advances, ...
Two major factors matter when it comes to cells copying DNA: getting everything accurate in the sequence and how much of it is replicated. Mistakes can result in mutations, which can lead to diseases such as cancer.
If asked about clones, most people think of evil sci-fi characters. However, in real life, the word "clone" often has broader, far more positive applications. Just as office workers replicate documents by using copy machines, ...
Researchers from Tokyo Metropolitan University and the FIRC Institute of Molecular Oncology (IFOM) in Italy have succeeded in depleting AND-1, a key protein for DNA replication, by using a recently developed conditional protein ...
DNA is a lengthy molecule—approximately 1,000-fold longer than the cell in which it resides—so it can't be jammed in haphazardly. Rather, it must be neatly organized so proteins involved in critical processes can access ...
If you've ever seen a picture of a DNA molecule, you probably saw it in its famous B-form: two strands coiling around each other in a right-handed fashion to form a double helix. But did you know that DNA can change its shape?
Jan 07, 2019
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