DNA is a lengthy molecule—approximately 1,000-fold longer than the cell in which it resides—so it can't be jammed in haphazardly. Rather, it must be neatly organized so proteins involved in critical processes can access ...
Cell & Microbiology
Sep 18, 2018
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A research collaboration between the Medical University of South Carolina, the Institute of Human Genetics in France, and Howard Hughes Medical Institute at Rockefeller University has revealed the means by which cells accomplish ...
Cell & Microbiology
Jun 14, 2016
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European scientists investigated the dynamic unfolding of DNA during replication by generating a tool that could subsequently be applied to screen helicase-targeting drugs for infection and oncologic applications.
Cell & Microbiology
Oct 4, 2012
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A team of Whitehead Institute scientists has discovered the surprising manner in which an enigmatic protein known as SUUR acts to control gene copy number during DNA replication. It's a finding that could shed new light on ...
Cell & Microbiology
Oct 30, 2014
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A team of researchers from the Biology department at the TU Darmstadt has identified an enzyme that separates DNA replication from repair. This discovery could be of tremendous significance in the treatment of tumours. The ...
Cell & Microbiology
Jun 3, 2016
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The body's cells are constantly dividing—which, somewhat counterintuitively, means that they're constantly multiplying. Because when a cell divides it doesn't split into two useless halves, but rather into two fully functional ...
Cell & Microbiology
Aug 8, 2019
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USC scientists have discovered how two different structural apparatuses collaborate to protect repetitive DNA when it is at its most vulnerable – while it is being unzipped for replication.
Cell & Microbiology
Mar 7, 2013
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New insights into the control of DNA replication and cell division in Corynebacterium glutamicum, a biotechnologically important microorganism, could help to optimize the industrial production of amino acids.
Cell & Microbiology
Jun 7, 2017
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