A new study in Science from Karolinska Institutet maps out how different DNA-binding proteins in human cells react to certain biochemical modifications of the DNA molecule. The scientists report that some 'master' regulatory ...
Biotechnology
May 4, 2017
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There are many processes that take place in cells that are essential for life. Two of these, transcription and translation, allow the genetic information stored in DNA to be deciphered into the proteins that form all living ...
Cell & Microbiology
Apr 13, 2017
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38
Humans have a lot in common with the humble sea sponge, according to research that changes the way we think about animal evolution.
Evolution
Apr 11, 2017
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8
Genome editing using CRISPR/Cas9 "gene scissors" is a powerful tool for biological discovery and for identifying novel drug targets. In pooled CRISPR screens, a large number of cells are edited simultaneously using CRISPR ...
Biotechnology
Jan 19, 2017
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Scientists at The University of Texas at Austin have observed for the first time that separate populations of the same species—in this case, coral—can diverge in their capacity to regulate genes when adapting to their ...
Environment
Nov 7, 2016
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310
Snakes lost their limbs over 100 million years ago, but scientists have struggled to identify the genetic changes involved. A Cell paper publishing October 20 sheds some light on the process, describing a stretch of DNA involved ...
Plants & Animals
Oct 20, 2016
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Scientists at the interface of biophysics, evolutionary biology and systems biology develop new framework to analyze effects of global crosstalk on gene regulation | interdisciplinary collaboration between three IST Austria ...
Cell & Microbiology
Aug 12, 2016
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393
Scientists from A*STAR's Genome Institute of Singapore (GIS) have discovered the unique functions of a specific type of histone modification, which may prove crucial in understanding gene regulation and the development of ...
Biotechnology
Jul 11, 2016
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24
(Phys.org)—A team of researchers with Massachusetts General Hospital, Harvard Medical School and the Broad Institute has developed a procedure to decode histone modifications that point out gene regulation. In their paper ...
RNA splicing is a major underlying factor that links mutations to complex traits and diseases, according to an exhaustive analysis of gene expression in whole genome and cell line data. Reporting in Science on April 29, 2016 ...
Cell & Microbiology
Apr 28, 2016
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