Scientists provide new insights into gene regulation

A team of researchers led by the University of Leicester has shed new light on how the regulation machinery that controls gene expression works by characterising a complex known as the NuRD complex.

Learning to program cellular memory

What if we could program living cells to do what we would like them to do in the body? Having such control—a major goal of synthetic biology—could allow for the development of cell-based therapies that might one day replace ...

Harbingers of aging

Midlife crisis in the insect world: In a new study, Ludwig-Maximilians-Universitaet (LMU) in Munich researchers have detected age-dependent alterations in metabolism and gene regulation in middle-aged fruitflies, and show ...

Mother controls embryo's gene activity

Frog embryos do not fully control which genes they can turn on or off in the beginning of their development – but their mother does, through specific proteins in the egg cell. Molecular developmental biologists at Radboud ...

New insights into cooperativity in gene regulation

In a study published in Nature, Dirk Schübeler and his group at the Friedrich Miescher Institute for Biomedical Research (FMI) describe how the interplay between transcription factors and epigenetic modifications of DNA ...

Error correction strategies of cells: Team proposes new hypothesis

Cells dynamically respond to environmental signals by turning appropriate sets of genes on or off. The "control system" that determines which genes need to be expressed at what time depends primarily on the interactions between ...

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