Dually noted: New CRISPR-Cas9 strategy edits genes two ways

The CRISPR-Cas9 system has been in the limelight mainly as a revolutionary genome engineering tool used to modify specific gene sequences within the vast sea of an organism's DNA. Cas9, a naturally occurring protein in the ...

Batting practice in the genome

In the biochemical game of genetics, it was thought that the proteins controlling gene regulation in animals were either spectators or players.

Unlocking fermentation secrets open the door to new biofuels

Researchers from the University of Illinois at Urbana-Champaign have, for the first time, uncovered the complex interdependence and orchestration of metabolic reactions, gene regulation, and environmental cues of clostridial ...

'Decoding' gene regulation

Researchers at the Max F. Perutz Laboratories of the University of Vienna and the Medical University of Vienna as well as at the University of Natural Resources and Life Sciences (BOKU) in Vienna have discovered an entirely ...

New light on bacterial microcompartments

Bacteria contain "microcompartments," which are poorly understood organelles that play critical roles in metabolism. Understanding how they work may ultimately enable engineering them for useful applications. In salmonella, ...

Chromosome-folding theory shows promise

Human chromosomes are much bigger and more complex than proteins, but like proteins, they appear to fold and unfold in an orderly process as they carry out their functions in cells.

DNA 'spool' modification affects aging and longevity

Research on a modified protein around which DNA is wrapped sheds light on how gene regulation is linked to aging and longevity in nematodes, fruit flies and possibly humans.

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