How organ functions were shaped over the course of evolution

A large-scale study conducted by molecular biologists from Heidelberg University has yielded groundbreaking new insights into the evolution and regulation of gene expression in mammalian organs. The scientists investigated ...

Desert algae shed light on desiccation tolerance in green plants

Deserts of the U.S. Southwest are extreme habitats for most plants, but, remarkably, microscopic green algae live there that are extraordinarily tolerant of dehydration. These tiny green algae (many just a few microns in ...

New tool probes gene regulation

DNA methylation (DNAme) is a modification of the genome—an epigenetic "mark"—that is required for proper cellular differentiation. It has been implicated in the regulation of gene expression, but its role in this stepwise ...

MicroRNA comprehensively analyzed

Messenger RNA transmits genetic information to the proteins, and microRNA plays a key role in the regulation of gene expression. Scientists from the Moscow Institute of Physics and Technology and the Research Centre for Medical ...

Orchestrating development in the fly embryo

Most multicellular organisms on Earth—including you—begin as a single fertilized egg and then undergo a complex choreography of cellular growth to become a functioning adult composed of countless cells. Understanding ...

Activating a new understanding of gene regulation

Regulation of gene expression—turning genes on or off, increasing or decreasing their expression—is critical for defining cell identity during development and coordinating cellular activity throughout the cell's lifetime. ...

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